{"id":"W2952014600","doi":"10.1016/j.ejpb.2019.06.013","title":"Dual delivery of nucleic acids and PEGylated-bisphosphonates via calcium phosphate nanoparticles","year":2019,"lang":"en","type":"article","venue":"European Journal of Pharmaceutics and Biopharmaceutics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Staatssekretariat für Bildung, Forschung und Innovation; Natural Sciences and Engineering Research Council of Canada; Singapore Eye Research Institute","keywords":"Transfection; Gene delivery; Chemistry; In vivo; Internalization; Drug delivery; Conjugate; Biophysics; Calcium; Nucleic acid; Biochemistry; Cell; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001970057,0.0004568728,0.0003088774,0.0002457202,0.0001781357,0.0005160251,0.0003450952,0.0006219359,0.000764225],"category_scores_gemma":[0.0001830471,0.0002509608,0.0002403223,0.0001466988,0.000297348,0.0004126634,0.0004337065,0.0004703382,0.0002774577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005751331,"about_ca_system_score_gemma":0.0004119274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006117013,"about_ca_topic_score_gemma":0.0006838119,"domain_scores_codex":[0.9998063,0.00001868403,0.00001236516,0.0000566917,0.00006087424,0.00004499952],"domain_scores_gemma":[0.9999219,0.00001414446,0.00002210562,0.000006592797,0.00001535437,0.00001985606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001245401,0.00001473313,0.00003205991,0.0000497634,0.000004744073,0.00004399196,0.00001257076,0.0001438528,0.9971204,0.0003266402,0.00003278712,0.002093999],"study_design_scores_gemma":[0.00001826461,0.00008088265,0.0001113402,0.000002509613,0.000009951892,0.00006264856,0.000004518398,0.0008861878,0.9976035,0.00004596476,0.001169896,0.00000429859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9728878,0.003212925,0.01790256,0.0002974028,0.0001241019,0.00008234496,0.0001190668,0.0002194116,0.005154476],"genre_scores_gemma":[0.9839055,0.0008249286,0.008943843,0.00007857569,0.00001843112,0.0000677781,0.00006460373,0.0000289471,0.006067411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000764225,"threshold_uncertainty_score":0.004172981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02096658013910725,"score_gpt":0.2742539664885308,"score_spread":0.2532873863494236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}