{"id":"W2952079965","doi":"10.1002/chin.201005279","title":"ChemInform Abstract: Ultrahigh‐Throughput FACS‐Based Screening for Directed Enzyme Evolution","year":2010,"lang":"en","type":"article","venue":"ChemInform","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Throughput; High-throughput screening; Enzyme; Computational biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002066599,0.0002407526,0.000189383,0.00005553223,0.0001488913,0.00005197514,0.0002448541,0.0003614097,0.0002029832],"category_scores_gemma":[0.0003278725,0.0002334008,0.0002002783,0.0001513646,0.00009161325,0.0000289141,0.00004575497,0.0001598234,0.00001373804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002788464,"about_ca_system_score_gemma":0.0001105872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001658187,"about_ca_topic_score_gemma":0.00004114279,"domain_scores_codex":[0.9987648,9.498455e-8,0.0003673278,0.0003407956,0.0001682498,0.0003587114],"domain_scores_gemma":[0.9989123,0.00002827181,0.0001918986,0.0004765489,0.000271913,0.0001190528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007796834,0.00004827864,0.00007534388,0.00006191636,0.00003713175,2.0293e-7,0.00005060216,0.000006649579,0.9300469,0.00008377333,0.01584631,0.05366489],"study_design_scores_gemma":[0.0007039984,0.00006070406,0.0009140116,0.00001292817,0.00002547796,0.000004170522,0.00006920438,0.0002586542,0.8173248,0.00001299642,0.1803495,0.0002636556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.3570861,0.000741501,0.004807596,0.0003743935,0.001582979,0.002422376,0.000482015,0.000558423,0.6319447],"genre_scores_gemma":[0.9855512,0.00001314651,0.001031464,0.0001923048,0.0004672629,0.0001348082,0.004133604,0.00003809549,0.008438057],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6284652,"threshold_uncertainty_score":0.9517809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211368145705071,"score_gpt":0.2503004801793232,"score_spread":0.2381867987222725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}