{"id":"W2952098942","doi":"10.1136/annrheumdis-2019-eular.1253","title":"FRI0401 EFFECT OF LONG-TERM TREATMENT WITH SECUKINUMAB ON LIPID PROFILE IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS AND PSORIATIC ARTHRITIS: POOLED 4 YEAR ANALYSIS","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Celgene; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Secukinumab; Ankylosing spondylitis; Psoriatic arthritis; Internal medicine; Lipid profile; Adalimumab; Gastroenterology; Placebo; Population; Concomitant; Statin; Adverse effect; Rheumatoid arthritis; Cholesterol; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007154448,0.001987923,0.006682344,0.001129681,0.0004267413,0.002056215,0.001191173,0.002115489,0.002661983],"category_scores_gemma":[0.005997015,0.001055805,0.02296873,0.001707491,0.0006295045,0.001492051,0.001178371,0.002236419,0.0003760979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009597482,"about_ca_system_score_gemma":0.0009516979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005362538,"about_ca_topic_score_gemma":0.008659351,"domain_scores_codex":[0.9960304,0.001875302,0.0005332319,0.0007672244,0.0004111712,0.0003826067],"domain_scores_gemma":[0.9959842,0.001640151,0.001171917,0.0005661462,0.0003514222,0.0002862396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.4227132,0.0003662353,0.09681424,0.004901197,0.4474908,0.0002862565,0.000102014,0.002023181,0.001899088,0.0001366458,0.001758358,0.02150882],"study_design_scores_gemma":[0.04370855,0.02770477,0.5147392,0.0006596386,0.4051732,0.0003903176,0.0002618192,0.002268781,0.0006867934,0.0003352077,0.003865546,0.0002062343],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8467617,0.1418315,0.001222081,0.0004719622,0.0008628791,0.0001639836,0.006630699,0.0001235518,0.001931577],"genre_scores_gemma":[0.9830737,0.01010569,0.0003936091,0.0004618824,0.000372433,0.0001194498,0.004108308,0.00002449578,0.001340473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007154448,"threshold_uncertainty_score":0.03783679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006685494126029679,"score_gpt":0.2494166671924556,"score_spread":0.2427311730664259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}