{"id":"W2952107331","doi":"10.1002/eji.201848026","title":"Multifunctional cytokine production reveals functional superiority of memory CD4 T cells","year":2019,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"H2020 European Research Council; Medical Research Council; Versus Arthritis; University of Glasgow; Arthritis Research UK","keywords":"Biology; Cytokine; Immunology; Cytotoxic T cell; Interleukin 21; IL-2 receptor; CD8; Memory T cell; T cell; Cell biology; ZAP70; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001472408,0.0003012015,0.0007389642,0.0004131015,0.0001474602,0.000009574991,0.0004915734,0.0002091801,0.003537778],"category_scores_gemma":[0.0001966564,0.0002557014,0.0003381765,0.0002255659,0.0006035991,0.0002373427,0.000186467,0.001036842,0.002353156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007613868,"about_ca_system_score_gemma":0.0001509799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000131595,"about_ca_topic_score_gemma":0.000001753475,"domain_scores_codex":[0.996304,0.00149964,0.001282825,0.0003643515,0.0001082344,0.0004409207],"domain_scores_gemma":[0.9975794,0.0001970276,0.001073028,0.000488191,0.0006312978,0.0000310643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001582792,0.0004226185,0.003462921,0.00003030858,0.0007476254,0.00003668258,0.000274336,0.0001167054,0.9870011,0.0001678439,0.003583512,0.002573529],"study_design_scores_gemma":[0.004290949,0.002080614,0.05590207,0.00009042676,0.0001183145,0.002818732,0.0005738821,0.000001033455,0.8751387,0.00006980469,0.05862195,0.0002935127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793652,0.004407183,0.000204274,0.0003881086,0.01251126,0.0002069744,0.00002032673,0.00003639585,0.002860232],"genre_scores_gemma":[0.9876804,0.0003096977,0.0002790049,0.00009865981,0.0002847382,0.000001568037,0.00004288703,0.00004217973,0.01126091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1118624,"threshold_uncertainty_score":0.9999895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01290436110841684,"score_gpt":0.198669294269147,"score_spread":0.1857649331607301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}