{"id":"W2952179143","doi":"10.1002/chin.200430298","title":"Structure‐Switching Signaling Aptamers: Transducing Molecular Recognition into Fluorescence Signaling","year":2004,"lang":"en","type":"article","venue":"ChemInform","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Aptamer; Fluorescence; Biophysics; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001480333,0.0002546061,0.0001956513,0.00007738952,0.0001519763,0.00005324053,0.0001896357,0.0002159497,0.000005430772],"category_scores_gemma":[0.0000644184,0.0002424196,0.0001676886,0.0001892724,0.00007103317,0.00001917217,0.00005278404,0.0001890693,0.000003204864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006511236,"about_ca_system_score_gemma":0.00006575257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002117795,"about_ca_topic_score_gemma":0.000009800056,"domain_scores_codex":[0.9987482,0.000002017072,0.0003229398,0.0004127672,0.0001976644,0.0003164294],"domain_scores_gemma":[0.9993356,0.000007004128,0.0001414058,0.0002947149,0.0001198629,0.0001013428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000303447,0.00001384113,0.000003811567,0.00002985863,0.00004387001,0.000006607611,0.0001752933,0.00005981898,0.9105062,0.000007149272,0.00001551695,0.08910771],"study_design_scores_gemma":[0.000323517,0.00008487154,0.000002161887,0.0001242743,0.00004873652,0.00002271204,0.0002112317,0.00002256001,0.9971917,0.001258123,0.0003497759,0.0003603096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907014,0.0001034276,0.007560426,0.0001078052,0.00006740432,0.0001563455,0.0000113453,0.0001067276,0.001185169],"genre_scores_gemma":[0.9615631,0.00004735769,0.03751275,0.0004226196,0.0001679718,0.000005813902,0.0002257756,0.00002974869,0.00002490823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0887474,"threshold_uncertainty_score":0.9885585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008407584647099557,"score_gpt":0.2453905157553805,"score_spread":0.236982931108281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}