{"id":"W2952191991","doi":"10.1002/chin.201038279","title":"ChemInform Abstract: Antibiotic Resistance by Enzyme Inactivation: From Mechanisms to Solutions","year":2010,"lang":"en","type":"article","venue":"ChemInform","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Antibiotics; Enzyme; Antibiotic resistance; Combinatorial chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001628411,0.000279708,0.0002154446,0.00004061816,0.0001709751,0.00008557495,0.0004708395,0.0003754749,0.0006014958],"category_scores_gemma":[0.0002448863,0.0002889334,0.00009678979,0.0001560817,0.000113124,0.00002934505,0.0001762444,0.0002469027,0.0001442513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005231304,"about_ca_system_score_gemma":0.0001173697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003332146,"about_ca_topic_score_gemma":0.0001542771,"domain_scores_codex":[0.9984514,1.384023e-7,0.0003918705,0.0004353368,0.0002388015,0.0004824318],"domain_scores_gemma":[0.9986464,0.00002461498,0.0001807796,0.0007829982,0.0001369117,0.0002282744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006339744,0.00003605273,0.00003497224,0.00001772909,0.00002673299,0.000001102823,0.0000501715,5.574392e-8,0.8396376,0.0004819167,0.1516197,0.00803053],"study_design_scores_gemma":[0.0002423798,0.00002670962,0.002153817,0.00002582088,0.00001031808,0.000003059309,0.000105045,6.708262e-7,0.7672129,0.0001875222,0.2297383,0.0002934564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.4170119,0.000155088,0.0001940127,0.0006853578,0.0008412995,0.0004950163,0.000381885,0.00009400163,0.5801414],"genre_scores_gemma":[0.9596747,0.00003428103,0.001673781,0.0005102739,0.0003394097,0.00001273106,0.000920368,0.00003876442,0.03679573],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5433457,"threshold_uncertainty_score":0.9999563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008650434982819944,"score_gpt":0.2307436681297434,"score_spread":0.2220932331469234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}