{"id":"W2952191991","doi":"10.1002/chin.201038279","title":"ChemInform Abstract: Antibiotic Resistance by Enzyme Inactivation: From Mechanisms to Solutions","year":2010,"lang":"en","type":"article","venue":"ChemInform","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Antibiotics; Enzyme; Antibiotic resistance; Combinatorial chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001208703,0.001585194,0.001364214,0.003229161,0.0008810406,0.002017069,0.001862275,0.003162647,0.03775978],"category_scores_gemma":[0.001915152,0.0006857916,0.000534702,0.004535594,0.001275628,0.003051414,0.0012844,0.004406468,0.04468362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002054496,"about_ca_system_score_gemma":0.001748594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001802441,"about_ca_topic_score_gemma":0.002599109,"domain_scores_codex":[0.9994379,0.00006161856,0.00004728795,0.0000857088,0.0003196456,0.00004777643],"domain_scores_gemma":[0.9981357,0.0004828622,0.0001328541,0.00007558323,0.0009720487,0.0002009421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000100891,0.00003656018,0.00007333289,0.006118443,0.00004567425,0.0001200025,0.00002233115,0.0002604215,0.001874411,0.01126826,0.7836434,0.1964363],"study_design_scores_gemma":[0.00001201658,0.00002397614,0.0001099815,0.0004437617,0.00002286471,0.0001824343,0.00001025305,0.00005178283,0.0008405523,0.001708914,0.9965814,0.00001212636],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002980427,0.9073197,0.001632661,0.01185098,0.02661427,0.00005331222,0.0005122161,0.0001965999,0.05152212],"genre_scores_gemma":[0.002703749,0.943082,0.0008282125,0.006000004,0.01041478,0.00005040699,0.0006470013,0.00004567566,0.03622819],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03775978,"threshold_uncertainty_score":0.1263191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008650434982819944,"score_gpt":0.2307436681297434,"score_spread":0.2220932331469234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}