{"id":"W2952217732","doi":"10.1016/j.cbi.2019.06.023","title":"Formic acid up-regulates vascular tension through nitric oxide-cGMP signaling pathway","year":2019,"lang":"en","type":"article","venue":"Chemico-Biological Interactions","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Natural Science Foundation of Shanxi Province; National Natural Science Foundation of China; Ontario Innovation Trust","keywords":"Formic acid; Vasodilation; Nitric oxide; Chemistry; Vasoconstriction; Enos; Pharmacology; Biochemistry; Prodrug; Internal medicine; Nitric oxide synthase; Medicine; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001167709,0.0002953376,0.0002398766,0.0001863396,0.0003272637,0.0002960996,0.0002201663,0.0004779914,0.002215482],"category_scores_gemma":[0.0002188893,0.0001292933,0.0002975826,0.00009389298,0.0002809806,0.0002974972,0.0002909623,0.0005149279,0.0002071933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003417007,"about_ca_system_score_gemma":0.0002802583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007824841,"about_ca_topic_score_gemma":0.001111297,"domain_scores_codex":[0.9998702,0.00002831863,0.00000774694,0.00002075161,0.0000264729,0.00004653917],"domain_scores_gemma":[0.999918,0.00001288526,0.00001839526,0.000004944788,0.00001315958,0.00003274128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004695684,0.0002798609,0.001481453,0.000207295,0.00004542016,0.0008062419,0.00007014474,0.0001638634,0.9839551,0.0005756239,0.0003691223,0.007350145],"study_design_scores_gemma":[0.0005047127,0.002955625,0.05400598,0.00005808999,0.0001634325,0.001047042,0.0005179182,0.003113399,0.9263319,0.001090022,0.01018079,0.00003106287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845545,0.008996779,0.001582324,0.0007066904,0.0002325985,0.00003130995,0.000191849,0.00004854918,0.003655446],"genre_scores_gemma":[0.9950571,0.001884959,0.0006131546,0.0001774461,0.00005381882,0.00001927814,0.0001331745,0.000004064052,0.002056948],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002215482,"threshold_uncertainty_score":0.00741148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03381288252119039,"score_gpt":0.284392705092301,"score_spread":0.2505798225711106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}