{"id":"W2952240310","doi":"10.1021/cc700159u","title":"Formation of Substituted Pyrroles via an Imine Condensation/Aza-Claisen Rearrangement/Imine−Allene Cyclization Process by MAOS","year":2007,"lang":"en","type":"article","venue":"Journal of Combinatorial Chemistry","topic":"Synthesis and Characterization of Pyrroles","field":"Chemistry","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Allene; Imine; Claisen rearrangement; Chemistry; Aldehyde; Domino; Amine gas treating; Condensation; Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005503946,0.0002292521,0.0004083713,0.00007626729,0.00009082346,0.0000510828,0.000342357,0.0002770436,0.0005693406],"category_scores_gemma":[0.0002093531,0.0002266604,0.0001257492,0.000170714,0.00009048694,0.000707527,0.00002256705,0.0002172813,0.000001980856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001146186,"about_ca_system_score_gemma":0.00008985546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003988168,"about_ca_topic_score_gemma":8.062606e-7,"domain_scores_codex":[0.9976513,0.00002119648,0.001194188,0.0001737492,0.0007313726,0.0002282255],"domain_scores_gemma":[0.9968867,0.00007904591,0.001653536,0.0002369289,0.0009619161,0.0001819301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004224023,0.0004411796,0.0006860403,0.000421728,0.00006013693,0.000006829991,0.0002917526,0.00003912083,0.9965693,0.00007376105,0.0003261362,0.0006616025],"study_design_scores_gemma":[0.002017298,0.00004405518,0.0002467505,0.0001720134,0.00009358419,0.00004394808,0.0006228696,0.0002859748,0.9948417,0.0007142798,0.0006994218,0.0002181032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994956,0.0001321064,0.002679361,0.0001260113,0.0003725901,0.00006280351,0.00003130479,0.0000341731,0.001605617],"genre_scores_gemma":[0.9985904,0.00007032874,0.0001050253,0.00001611608,0.0008358689,0.000003372458,0.0002517969,0.00003194967,0.00009515812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003634352,"threshold_uncertainty_score":0.9242941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009108399748783656,"score_gpt":0.2496453765180726,"score_spread":0.2405369767692889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}