{"id":"W2952240310","doi":"10.1021/cc700159u","title":"Formation of Substituted Pyrroles via an Imine Condensation/Aza-Claisen Rearrangement/Imine−Allene Cyclization Process by MAOS","year":2007,"lang":"en","type":"article","venue":"Journal of Combinatorial Chemistry","topic":"Synthesis and Characterization of Pyrroles","field":"Chemistry","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Allene; Imine; Claisen rearrangement; Chemistry; Aldehyde; Domino; Amine gas treating; Condensation; Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002738253,0.0004485935,0.0002949639,0.0002368915,0.0001471427,0.000269774,0.0003156722,0.0001936543,0.00130597],"category_scores_gemma":[0.0002764606,0.0001983396,0.0002958079,0.0001458626,0.000128842,0.0003027722,0.000208585,0.0003655187,0.0004650067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002383053,"about_ca_system_score_gemma":0.0001829096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002529395,"about_ca_topic_score_gemma":0.0006382776,"domain_scores_codex":[0.9998254,0.0000249603,0.0000213575,0.00004556062,0.00004363529,0.00003912624],"domain_scores_gemma":[0.9998846,0.00001705642,0.00003332689,0.00001971617,0.00001906223,0.00002615536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007849856,0.00002304495,0.00007943706,0.00007743767,0.0000119308,0.0001700608,0.00004611353,0.0002254099,0.9952473,0.0002794529,0.00005768701,0.003703622],"study_design_scores_gemma":[0.00001667882,0.0002975856,0.0005933525,0.000003842451,0.00001400299,0.0002503827,0.000007761358,0.0005303893,0.9959822,0.0000420587,0.002254136,0.000007712741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976767,0.001759796,0.0134421,0.00006518962,0.00004159212,0.0002022081,0.0005705752,0.000245774,0.006905742],"genre_scores_gemma":[0.9859965,0.0008129756,0.0103819,0.00002069427,0.00001116988,0.00007162864,0.0002788454,0.00002898937,0.002397234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00130597,"threshold_uncertainty_score":0.004368901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009108399748783656,"score_gpt":0.2496453765180726,"score_spread":0.2405369767692889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}