{"id":"W2952256516","doi":"10.1002/chin.200107104","title":"ChemInform Abstract: Parallel Synthesis of Isatin‐Based Serine Protease Inhibitors.","year":2001,"lang":"en","type":"article","venue":"ChemInform","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BioPhage Pharma (Canada)","funders":"","keywords":"Chemistry; Isatin; Combinatorial chemistry; Serine protease; Information retrieval; Protease; Organic chemistry; Computer science; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004395849,0.001113101,0.0006979573,0.000719414,0.0002772631,0.0005968431,0.000577067,0.0003172486,0.01154798],"category_scores_gemma":[0.0003067077,0.0003757902,0.0004723888,0.0007607,0.0001694917,0.0006941699,0.0004119898,0.0009208175,0.006268946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006777236,"about_ca_system_score_gemma":0.001051868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006315251,"about_ca_topic_score_gemma":0.00113541,"domain_scores_codex":[0.9997051,0.00003159843,0.00001975426,0.00006172139,0.000121024,0.00006062568],"domain_scores_gemma":[0.999912,0.000008000244,0.00001731474,0.00001210959,0.00002090126,0.0000297678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001681771,0.0003178502,0.0001641711,0.0009388635,0.0001706709,0.0003466189,0.00009645986,0.003350238,0.7987354,0.005452057,0.03276073,0.1559852],"study_design_scores_gemma":[0.0004249341,0.001038747,0.0005472102,0.00003958821,0.0001222706,0.0005388489,0.0000225461,0.004696469,0.8571753,0.001267063,0.1340892,0.00003772202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3358138,0.04457859,0.380509,0.002386795,0.004589735,0.0023126,0.02560113,0.01398271,0.1902257],"genre_scores_gemma":[0.6116117,0.03294054,0.2224497,0.0006770605,0.0004603912,0.0008673033,0.0302122,0.001607906,0.09917304],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01154798,"threshold_uncertainty_score":0.03863186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009411800643199703,"score_gpt":0.2276040095549942,"score_spread":0.2181922089117945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}