{"id":"W2952294434","doi":"10.1097/01.hs9.0000561352.05716.6c","title":"PF767 PHASE 2 STUDY EVALUATING THE SAFETY AND EFFICACY OF ONE OR TWO DOSES OF DONOR LYMPHOCYTES DEPLETED OF HOST ALLOREACTIVE T‐CELLS (ATIR101) FOLLOWING T‐CELL‐DEPLETED HAPLOIDENTICAL HSCT","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Medicine; Hematopoietic stem cell transplantation; Graft-versus-host disease; Immunosuppression; Immune system; T cell; Immunology; Ex vivo; CD34; Stem cell; Transplantation; Haematopoiesis; Clinical endpoint; Internal medicine; Gastroenterology; In vivo; Clinical trial; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001674253,0.001777385,0.001637231,0.0004895402,0.0003524695,0.0008934567,0.0008048555,0.001606451,0.003121918],"category_scores_gemma":[0.0009396645,0.0004857381,0.0008297209,0.0003444433,0.001250296,0.000772709,0.0002795239,0.003188834,0.0008597649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000932864,"about_ca_system_score_gemma":0.001819943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006178304,"about_ca_topic_score_gemma":0.001295855,"domain_scores_codex":[0.9995937,0.0001886709,0.00001641656,0.00007491901,0.00003543689,0.0000908704],"domain_scores_gemma":[0.9993253,0.0001336835,0.0001330048,0.00006331485,0.00003939212,0.000305329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6844555,0.1309647,0.004360229,0.0007758406,0.0009067866,0.0005991766,0.0003380739,0.006624735,0.08923262,0.0006210823,0.004543105,0.07657824],"study_design_scores_gemma":[0.2880372,0.6986648,0.003771741,0.00002541407,0.0002368805,0.0003334691,0.00004199997,0.001035998,0.005924508,0.0001829703,0.00171885,0.00002611942],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938017,0.0008726553,0.0006143051,0.000285874,0.0001115515,0.002130192,0.0008216572,0.00009296071,0.001269072],"genre_scores_gemma":[0.9874462,0.001016964,0.001692962,0.0006565503,0.0001516962,0.003617674,0.002609029,0.00002639287,0.002782517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003121918,"threshold_uncertainty_score":0.01044387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05400656725039787,"score_gpt":0.3857418889832553,"score_spread":0.3317353217328574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}