{"id":"W2952294434","doi":"10.1097/01.hs9.0000561352.05716.6c","title":"PF767 PHASE 2 STUDY EVALUATING THE SAFETY AND EFFICACY OF ONE OR TWO DOSES OF DONOR LYMPHOCYTES DEPLETED OF HOST ALLOREACTIVE T‐CELLS (ATIR101) FOLLOWING T‐CELL‐DEPLETED HAPLOIDENTICAL HSCT","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Medicine; Hematopoietic stem cell transplantation; Graft-versus-host disease; Immunosuppression; Immune system; T cell; Immunology; Ex vivo; CD34; Stem cell; Transplantation; Haematopoiesis; Clinical endpoint; Internal medicine; Gastroenterology; In vivo; Clinical trial; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001430018,0.0003305808,0.001227931,0.0001145988,0.00009102823,0.00002296382,0.0002966238,0.0001146472,0.002383382],"category_scores_gemma":[0.0007866406,0.0002249508,0.0003109931,0.0006361714,0.0002799543,0.0001156312,0.0002297818,0.00033226,0.00001510562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001457838,"about_ca_system_score_gemma":0.0004555653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006354032,"about_ca_topic_score_gemma":0.0000856578,"domain_scores_codex":[0.9961951,0.000448305,0.001038649,0.0005411802,0.001329363,0.0004473445],"domain_scores_gemma":[0.9950936,0.002958792,0.0004507282,0.0009039987,0.0004232746,0.0001695573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01586554,0.003129796,0.01755258,0.0004700696,0.00105582,0.0000303826,0.00382879,0.00002017809,0.9482834,0.00002405671,0.00001899476,0.0097204],"study_design_scores_gemma":[0.06852896,0.01294674,0.02396086,0.0008706689,0.001223924,0.00002515662,0.01334419,0.003632822,0.8749894,0.00002440653,0.0000972741,0.0003555719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993551,0.0008432067,0.00004798903,0.00006893215,0.0001004703,0.003357177,0.0000303481,0.00003432334,0.001966581],"genre_scores_gemma":[0.9975143,0.00006927374,0.0007551824,0.0000355548,0.00006648757,0.0000331416,0.00001699898,0.00007798863,0.001431056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07329397,"threshold_uncertainty_score":0.9985286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05400656725039787,"score_gpt":0.3857418889832553,"score_spread":0.3317353217328574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}