{"id":"W2952314547","doi":"10.1371/journal.pgen.1004622","title":"Evidence for Widespread Positive and Negative Selection in Coding and Conserved Noncoding Regions of Capsella grandiflora","year":2014,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":185,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto","funders":"Genome Canada; National Science Foundation","keywords":"Negative selection; Biology; Genome; Genetics; Evolutionary biology; Selection (genetic algorithm); Coding region; Gene; Conserved sequence; Brassicaceae; Computational biology; Ecology; Base sequence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001290775,0.0002770609,0.0001672639,0.0005110828,0.0002792708,0.0002737459,0.0001570758,0.0002119015,0.0005522599],"category_scores_gemma":[0.0002217248,0.0001542538,0.000155818,0.0003545795,0.0002987481,0.0001581247,0.0002154382,0.0002163775,0.0001091329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001879816,"about_ca_system_score_gemma":0.0001958455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003336509,"about_ca_topic_score_gemma":0.00823653,"domain_scores_codex":[0.9999132,0.000008319201,0.000005297778,0.00004157265,0.00001871763,0.00001292268],"domain_scores_gemma":[0.9997396,0.0000729924,0.00007366668,0.00002646109,0.00003987299,0.00004740655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008821588,0.000006223925,0.0199462,0.00005613753,0.00001894265,0.00007540648,0.0001825425,0.00009926478,0.9761603,0.00007263288,0.00002868835,0.003265494],"study_design_scores_gemma":[0.00001003547,0.0001005981,0.9583045,0.00001313633,0.00004987041,0.0005152528,0.0002574367,0.0006452107,0.03821655,0.0001731763,0.001695663,0.00001859963],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987294,0.0003404479,0.0002950013,0.00002532654,0.000002190865,0.000001861689,0.0002048306,0.00001934405,0.0003816614],"genre_scores_gemma":[0.9982935,0.0001485195,0.000521536,0.00004201298,0.000003623433,0.000006126845,0.0006621928,0.000009633449,0.000312963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003336509,"threshold_uncertainty_score":0.006634176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05280666350839595,"score_gpt":0.2771262555600887,"score_spread":0.2243195920516927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}