{"id":"W2952340909","doi":"10.1021/ol052069n","title":"Electrophilic Activation of Lactams with Tf<sub>2</sub>O and Pyridine:  Expedient Synthesis of (±)-Tetraponerine T4","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Advanced Synthetic Organic Chemistry","field":"Chemistry","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Pyridinium; Electrophile; Pyridine; Yield (engineering); Nucleophile; Reagent; Combinatorial chemistry; Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007122204,0.0002505107,0.0003509088,0.00004198654,0.00004117954,0.000008068184,0.0001832329,0.0001021003,0.0003604049],"category_scores_gemma":[0.0001591232,0.0002321016,0.00005206102,0.0002002073,0.0001837366,0.0001258913,0.00005957727,0.0001959625,0.000004545288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001694251,"about_ca_system_score_gemma":0.00004802343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003978908,"about_ca_topic_score_gemma":0.000002622624,"domain_scores_codex":[0.9986559,0.00001190315,0.0003607987,0.0003627526,0.0003141414,0.0002945766],"domain_scores_gemma":[0.9989263,0.0001827033,0.0003030675,0.0004507952,0.00004959449,0.00008756742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009005693,0.00009957191,0.0002523322,0.0002012632,0.00008845872,0.000003701385,0.0001796438,0.00001971568,0.994662,0.000006970138,0.000130767,0.004265504],"study_design_scores_gemma":[0.000527011,0.00002626397,0.0001048049,0.0001300835,0.00006823774,0.00004749021,0.0001146865,0.00003656325,0.998571,0.000006156333,0.0001347864,0.0002329106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974974,0.00006115916,0.0003488183,0.00165266,0.00001307923,0.00006423805,0.00001037844,0.00005991549,0.0002923263],"genre_scores_gemma":[0.9990303,0.00009645543,0.0004937397,0.0001183653,0.0001574466,0.00001190313,0.000007942706,0.0000681493,0.00001571349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004032593,"threshold_uncertainty_score":0.9464829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003415851181835035,"score_gpt":0.179794498695281,"score_spread":0.176378647513446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}