{"id":"W2952370447","doi":"10.1016/j.wneu.2019.06.043","title":"Risk of Adverse Vascular Events in Patients with Malignant Glioma Treated with Bevacizumab Plus Irinotecan: A Systematic Review and Meta-Analysis","year":2019,"lang":"en","type":"review","venue":"World Neurosurgery","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China; Heilongjiang Postdoctoral Science Foundation","keywords":"Medicine; Bevacizumab; Irinotecan; Glioma; Adverse effect; Meta-analysis; Oncology; Internal medicine; Surgery; Cancer; Chemotherapy; Colorectal cancer; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.0005500746,0.0009675503,0.01627222,0.002011861,0.0000404585,0.000008639963,0.0001561927,0.0001233928,0.00008303777],"category_scores_gemma":[0.0001319315,0.0004825781,0.003146298,0.004016688,0.00005992971,0.00007369209,0.00007598,0.0003090441,0.00002142504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002013416,"about_ca_system_score_gemma":0.0001819768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001584754,"about_ca_topic_score_gemma":0.0001023624,"domain_scores_codex":[0.9948099,0.0009891416,0.001891379,0.001014238,0.0008795887,0.0004157677],"domain_scores_gemma":[0.9952347,0.0005685424,0.002153013,0.001643936,0.0001864067,0.0002133926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00009698183,0.001053174,0.02750234,0.757118,0.2132083,0.0006496422,0.000008614003,0.00001101695,2.287971e-8,0.000001818561,0.00002438856,0.0003257174],"study_design_scores_gemma":[0.001639894,0.0003376029,0.006425707,0.1049187,0.885327,0.00005089573,0.000001324246,0.000001928671,0.000001026157,1.657564e-7,0.0009170053,0.0003787052],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008207443,0.9833503,7.295519e-7,0.00002012532,0.0000216386,0.008083229,0.0002751632,0.00002613488,0.00001520394],"genre_scores_gemma":[0.01529524,0.9825926,0.00001923375,0.0001018298,0.000004904547,0.001372715,0.000299704,0.0001177425,0.0001960113],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6721188,"threshold_uncertainty_score":0.9997626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03662687308628487,"score_gpt":0.2741856226469604,"score_spread":0.2375587495606755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}