{"id":"W2952389760","doi":"10.1021/jo8017236","title":"Synthesis of Annulated 2<i>H</i>-Indazoles and 1,2,3- and 1,2,4-Triazoles via a One-Pot Palladium-Catalyzed Alkylation/Direct Arylation Reaction","year":2008,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Annulation; Palladium; Aryl; Norbornene; Chemistry; Catalysis; Alkylation; Ring (chemistry); Alkyl; Medicinal chemistry; Coupling reaction; Combinatorial chemistry; Organic chemistry; Copolymer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001386483,0.0002871567,0.0002501085,0.0001506697,0.0001136397,0.0001385621,0.0003348336,0.0002007117,0.001740816],"category_scores_gemma":[0.0001210014,0.0001613877,0.0001789046,0.0001997375,0.000133598,0.0002103735,0.0001490726,0.0004080494,0.0006018055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002338614,"about_ca_system_score_gemma":0.0002460404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003692306,"about_ca_topic_score_gemma":0.001112611,"domain_scores_codex":[0.9999264,0.000009078469,0.000007720236,0.00001651337,0.00001710729,0.00002299069],"domain_scores_gemma":[0.9999543,0.0000056731,0.00001441262,0.000006053064,0.000008308141,0.00001114602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007923168,0.00003491363,0.00009735398,0.0001105178,0.000008269093,0.0001626712,0.00004588789,0.0003025229,0.9913648,0.0004880463,0.0001578194,0.00714803],"study_design_scores_gemma":[0.00004134512,0.0004283842,0.0009187742,0.000006239507,0.00001695514,0.0004409128,0.00001357492,0.0008068798,0.9890457,0.00008839095,0.008180099,0.0000127644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9497473,0.004769112,0.02657492,0.000189551,0.0001042908,0.000180068,0.0008006041,0.000533275,0.01710092],"genre_scores_gemma":[0.9744341,0.002722129,0.01699771,0.0001128586,0.00002053476,0.0000712818,0.0004884957,0.00003904106,0.005113843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001740816,"threshold_uncertainty_score":0.005823612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01711402648092068,"score_gpt":0.2332732123729087,"score_spread":0.2161591858919881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}