{"id":"W2952473657","doi":"10.82308/51629","title":"IL-10 reduces CD8 T cell antigen sensitivity during the establishment of chronic viral infection by modifying N-glycan branching","year":2017,"lang":"en","type":"article","venue":"eScholarship@McGill (McGill)","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto; Public Health Agency; National Institutes of Health; Public Health Agency of Canada; Faculty of Medicine, McGill University; McGill University; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"CD8; T cell; Biology; Glycan; Immunology; Antigen; Immune system; Cell biology; Glycoprotein; Molecular biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.001052678,0.0003789834,0.0004923159,0.0001132329,0.003638767,0.00008123609,0.0004834361,0.0004277067,0.0002094653],"category_scores_gemma":[0.0002348896,0.000316325,0.0002258618,0.000112646,0.0004109066,0.0006089917,0.0004340539,0.000963914,0.00009515609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004108779,"about_ca_system_score_gemma":0.00004716172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003371513,"about_ca_topic_score_gemma":0.001284627,"domain_scores_codex":[0.9973521,0.0006515712,0.0004952819,0.0006726958,0.0001024547,0.0007259423],"domain_scores_gemma":[0.9981154,0.000139716,0.000681459,0.0008700584,0.0001373197,0.00005605304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001458027,0.0001461958,0.001972313,0.00006577837,0.00014661,0.000006908999,0.00001190197,0.00004069911,0.9568344,0.000475789,0.0000157645,0.04013782],"study_design_scores_gemma":[0.001329441,0.00026697,0.02296554,0.00007519513,0.0000556507,0.00008173002,0.00003919192,0.00001042407,0.9422011,0.0002686789,0.03234956,0.0003565039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896811,0.0008489628,0.000001232636,0.00005165083,0.001318663,0.0003607598,0.0004778135,0.00009757414,0.007162226],"genre_scores_gemma":[0.9977376,0.0005188948,0.00001647349,0.00005067536,0.00005774475,0.00003352388,0.00005534428,0.00004458201,0.00148514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03978131,"threshold_uncertainty_score":0.9999289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01060020751677829,"score_gpt":0.2275337737289429,"score_spread":0.2169335662121646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}