{"id":"W2952488211","doi":"10.1371/journal.pgen.1006815","title":"Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function","year":2017,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; National Alliance for Research on Schizophrenia and Depression; York University; G. Harold and Leila Y. Mathers Charitable Foundation; Sleep Research Society; Leon Levy Foundation; New York University; Whitehall Foundation; Howard Hughes Medical Institute; Sleep Research Society Foundation; Alfred P. Sloan Foundation; Brain and Behavior Research Foundation","keywords":"Biology; Sleep (system call); Drosophila melanogaster; Neuroscience; Ubiquitin ligase; Mutant; Ubiquitin; Conserved sequence; Nervous system; Genetics; Gene; Cell biology; Peptide sequence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005659699,0.0002746675,0.0001501448,0.0004346869,0.0001802186,0.0001663519,0.0001557881,0.0001943645,0.0009011388],"category_scores_gemma":[0.00008654413,0.0001246493,0.000254803,0.0001379699,0.0001752399,0.0001331799,0.0003283513,0.0003380176,0.0002775211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000433814,"about_ca_system_score_gemma":0.0001489434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001788015,"about_ca_topic_score_gemma":0.002869203,"domain_scores_codex":[0.9999394,0.000004560805,0.000007529528,0.00001880526,0.00001837734,0.00001136514],"domain_scores_gemma":[0.9999084,0.000005288687,0.00004142874,0.000009355162,0.00001138004,0.00002413093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004174473,0.000006061303,0.001327815,0.00004520086,0.000009735861,0.0001780068,0.00001827242,0.00006005963,0.9963278,0.000234549,0.00007900263,0.001671765],"study_design_scores_gemma":[0.00004190875,0.0002513466,0.3558111,0.00004167488,0.00007626196,0.005069918,0.0001102701,0.003250276,0.6222244,0.0005652251,0.01252193,0.00003574896],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889529,0.00294104,0.003500727,0.0001170758,0.00002196427,0.0000214699,0.001001483,0.0002009897,0.003242451],"genre_scores_gemma":[0.9936928,0.0007701528,0.002536324,0.0001014561,0.000007488552,0.00001984722,0.001009263,0.00003738535,0.001825428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001788015,"threshold_uncertainty_score":0.003555238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08906971603607845,"score_gpt":0.2718926265411005,"score_spread":0.1828229105050221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}