{"id":"W2952512469","doi":"10.1002/chin.200712276","title":"Structure‐Based Organic Synthesis of Drug Prototypes: A Personal Odyssey","year":2007,"lang":"en","type":"article","venue":"ChemInform","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Personal account; Organic synthesis; Service (business); Nanotechnology; Combinatorial chemistry; Organic chemistry; Literature; Business; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007829664,0.0006504826,0.0003533832,0.0005235269,0.00064444,0.001057046,0.0006050394,0.0005654656,0.0302563],"category_scores_gemma":[0.0006746143,0.00054699,0.0005185187,0.0002965494,0.0007976597,0.002216608,0.001066946,0.001623047,0.009495704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006340327,"about_ca_system_score_gemma":0.0006860053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000462587,"about_ca_topic_score_gemma":0.001070684,"domain_scores_codex":[0.9996994,0.00005195271,0.00001324004,0.00005043658,0.0001500056,0.00003498207],"domain_scores_gemma":[0.9998443,0.00003800869,0.00001378454,0.00003520175,0.00002956661,0.00003908007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004745677,0.0006171465,0.0002162974,0.001191038,0.00007426692,0.0004618959,0.0005358548,0.002499366,0.2919978,0.08899586,0.1451919,0.467744],"study_design_scores_gemma":[0.0001853303,0.00188665,0.0003559281,0.0001850841,0.00003756037,0.000980406,0.0001271737,0.002359359,0.1787911,0.02389184,0.7911359,0.00006368064],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"commentary","genre_scores_codex":[0.05426612,0.1752984,0.3810171,0.02932543,0.009960736,0.000966227,0.00247936,0.006862267,0.3398244],"genre_scores_gemma":[0.2666371,0.1725964,0.175615,0.00726329,0.002516503,0.0006491153,0.001673193,0.001573436,0.3714761],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.0302563,"threshold_uncertainty_score":0.1012174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004561747090854243,"score_gpt":0.2175047775894832,"score_spread":0.2129430304986289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}