{"id":"W2952612948","doi":"10.1002/chin.200110159","title":"ChemInform Abstract: N,N‐Diethyl‐4‐(phenylpiperidin‐4‐ylidenemethyl)benzamide: A Novel, Exceptionally Selective, Potent δ Opioid Receptor Agonist with Oral Bioavailability and Its Analogues.","year":2001,"lang":"en","type":"article","venue":"ChemInform","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Chemistry; Benzamide; Bioavailability; Agonist; Stereochemistry; Pharmacology; Combinatorial chemistry; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001101812,0.0006716612,0.0003379981,0.0002519971,0.0002129895,0.0002548718,0.000555781,0.0002977835,0.01744368],"category_scores_gemma":[0.00009216459,0.0002339595,0.000141739,0.0001988124,0.000162912,0.0005115723,0.0002702887,0.0006535206,0.006715813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003479691,"about_ca_system_score_gemma":0.0004465626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006414069,"about_ca_topic_score_gemma":0.0008441657,"domain_scores_codex":[0.9999456,0.000005656142,0.000002726282,0.00001294117,0.00001946688,0.0000135874],"domain_scores_gemma":[0.9999759,0.000002387062,0.00000603162,0.000001733614,0.00000325312,0.00001070889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001909786,0.0003299274,0.000164824,0.001802452,0.00006142802,0.0009544631,0.00006159826,0.0008502912,0.7821434,0.004446086,0.04022,0.1670557],"study_design_scores_gemma":[0.0007990976,0.002344354,0.001950706,0.00008138891,0.0001058512,0.001846655,0.00002427127,0.001420828,0.8074524,0.0006528968,0.1832751,0.00004644354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4731064,0.1003745,0.07636968,0.005426995,0.004557405,0.001072633,0.01026585,0.005032308,0.3237942],"genre_scores_gemma":[0.7647018,0.04375652,0.01346901,0.001063814,0.0007314521,0.0003104849,0.0065537,0.0002033351,0.1692099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01744368,"threshold_uncertainty_score":0.05835497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03674687766624034,"score_gpt":0.2585689325785379,"score_spread":0.2218220549122976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}