{"id":"W2952617971","doi":"10.1136/annrheumdis-2019-eular.1873","title":"FRI0470 EFFECT OF DISCONTINUATION OF DENOSUMAB IN SUBJECTS WITH RHEUMATOID ARTHRITIS TREATED WITH GLUCOCORTICOIDS","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Bone health and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Denosumab; Medicine; Discontinuation; Rheumatoid arthritis; Internal medicine; Placebo; Osteoporosis; N-terminal telopeptide; Urology; Interim analysis; Gastroenterology; Randomized controlled trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009539492,0.0005355403,0.001815221,0.0003426395,0.0003810863,0.0007581554,0.0004038615,0.0009234353,0.003430204],"category_scores_gemma":[0.002829582,0.000215568,0.001746802,0.0003010621,0.0003023752,0.0003736879,0.0002634394,0.001516683,0.0004557719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004341849,"about_ca_system_score_gemma":0.0009197215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00635318,"about_ca_topic_score_gemma":0.01107212,"domain_scores_codex":[0.9994085,0.0002154294,0.00004422608,0.0000700533,0.00007629107,0.0001855671],"domain_scores_gemma":[0.9985412,0.0005453659,0.0003324346,0.00008058855,0.00008416308,0.0004161818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7958578,0.00452221,0.09240818,0.0008172125,0.005459539,0.0006037493,0.0001959892,0.000612983,0.0122175,0.0001584619,0.002628355,0.08451797],"study_design_scores_gemma":[0.03292346,0.1036951,0.8506262,0.0001706469,0.004382927,0.0007177278,0.0003464831,0.0007477992,0.001228145,0.0001564529,0.004943782,0.00006136297],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814596,0.01381104,0.00006038689,0.0004828497,0.0003119244,0.00004403878,0.001042129,0.0000314737,0.002756567],"genre_scores_gemma":[0.9951918,0.001901336,0.00007044001,0.0002910153,0.0002822972,0.00001719688,0.0008948059,0.000005185238,0.001345954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00635318,"threshold_uncertainty_score":0.01263237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109828730341636,"score_gpt":0.2715929719001931,"score_spread":0.2606100988660295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}