{"id":"W2952633152","doi":"10.1002/chin.200451111","title":"Synthesis of Functionalized 1‐Azaspirocyclic Cyclopentanones Using Broensted Acid or N‐Bromosuccinimide Promoted Ring Expansions.","year":2004,"lang":"en","type":"article","venue":"ChemInform","topic":"Asymmetric Synthesis and Catalysis","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; N-Bromosuccinimide; Ring (chemistry); Organic chemistry; Medicinal chemistry; Halogenation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001526328,0.0003369587,0.0006105517,0.0001986398,0.0001765063,0.00003597094,0.0003664235,0.0002258908,0.002254936],"category_scores_gemma":[0.0007985042,0.0002769391,0.0003028919,0.0007636321,0.0001098958,0.0002841121,0.0001456675,0.0001587632,0.00003074185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003191105,"about_ca_system_score_gemma":0.0001979692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001778222,"about_ca_topic_score_gemma":0.0000128782,"domain_scores_codex":[0.9979105,0.000001201412,0.000793831,0.0003773083,0.0005051674,0.000411979],"domain_scores_gemma":[0.9984243,0.0002190416,0.0004503619,0.0006175003,0.0001216418,0.0001671452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004311992,0.0003848979,0.0005534019,0.0006163925,0.0005301548,0.00003342603,0.000409695,0.00005412094,0.4906024,0.00005803383,0.0001504231,0.5061759],"study_design_scores_gemma":[0.0009920601,0.00001305384,0.0002530284,0.000394589,0.0002672699,0.00008846525,0.001112095,0.00005806024,0.9948308,0.00003830882,0.001609019,0.0003431837],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.702848,0.0003636116,0.00006279187,0.00005645281,0.00008735906,0.0001533934,0.00005089222,0.0001857403,0.2961918],"genre_scores_gemma":[0.995981,0.00008041339,0.001383449,0.00003469485,0.0001102753,0.0000577271,0.00005103899,0.00005146997,0.00224987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5058327,"threshold_uncertainty_score":0.9999683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.025478568269135,"score_gpt":0.2513804863139884,"score_spread":0.2259019180448534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}