{"id":"W2952644065","doi":"10.1097/01.hs9.0000559996.44290.19","title":"PF446 EVALUATING EX VIVO EXPANSION OF FUNCTIONALLY COMPETENT MULTI-SPECIFIC T LYMPHOCYTES TO MINOR HISTOCOMPATIBILITY ANTIGEN FOR THE TREATMENT OF HEMATOLOGICAL MALIGNANCIES","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Minor histocompatibility antigen; Immunology; CD8; T cell; Cytotoxic T cell; Stem cell; Priming (agriculture); Antigen; Haematopoiesis; Major histocompatibility complex; Biology; Cancer research; Immune system; Medicine; In vitro; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000166064,0.0003081755,0.000152544,0.0001443267,0.0000784985,0.0001470413,0.0001543507,0.0002519603,0.002354509],"category_scores_gemma":[0.0001065827,0.00004904563,0.0001561353,0.00008135779,0.00008291342,0.000133895,0.0001273962,0.000519595,0.0004269956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009360931,"about_ca_system_score_gemma":0.0001134012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007734056,"about_ca_topic_score_gemma":0.00009393739,"domain_scores_codex":[0.9999185,0.00002451698,0.000006107946,0.00001128425,0.00001934851,0.00002039077],"domain_scores_gemma":[0.9999537,0.00001278125,0.000009143344,0.000005030525,0.00000704851,0.0000121887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004207897,0.0005261432,0.0002336165,0.00008717214,0.000006054328,0.00006067829,0.00001957803,0.0004995939,0.9897231,0.0001072465,0.0001380428,0.008178038],"study_design_scores_gemma":[0.0002278265,0.009842036,0.001583319,0.00001411804,0.00005007458,0.0004889949,0.0000138065,0.001969142,0.9812043,0.00007921337,0.004522294,0.000004860206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917413,0.001479007,0.004573967,0.00008645649,0.00005248294,0.0001695036,0.0001803999,0.0000664383,0.001650477],"genre_scores_gemma":[0.9903451,0.0008847757,0.005973997,0.00006763826,0.00003708088,0.0001850349,0.0006081534,0.00001928282,0.001879051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002354509,"threshold_uncertainty_score":0.007876575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1249127160441747,"score_gpt":0.3660182318152017,"score_spread":0.241105515771027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}