{"id":"W2952644505","doi":"10.7150/jca.31241","title":"Exosomes from Macrophages Exposed to Apoptotic Breast Cancer Cells Promote Breast Cancer Proliferation and Metastasis","year":2019,"lang":"en","type":"article","venue":"Journal of Cancer","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; National Science Foundation","keywords":"Microvesicles; Metastasis; Cancer research; MMP2; Breast cancer; MMP9; STAT3; Exosome; Cancer cell; Apoptosis; Medicine; Cancer; Tumor microenvironment; Biology; Immunology; microRNA; Downregulation and upregulation; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001464782,0.0002204384,0.0003056692,0.00007191929,0.0000511259,0.00007572331,0.0002202404,0.0001061901,0.0006430761],"category_scores_gemma":[0.000009914318,0.0001835791,0.0001255754,0.000105503,0.00004624975,0.00002996093,0.00008450759,0.0001451578,0.000008377542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009197342,"about_ca_system_score_gemma":0.0003278799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001367019,"about_ca_topic_score_gemma":0.0001504918,"domain_scores_codex":[0.9986542,0.0000740927,0.0003822159,0.0003216546,0.0003074087,0.0002603903],"domain_scores_gemma":[0.9988306,0.00001026385,0.0003306496,0.0002497067,0.0003159631,0.0002627996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006106901,0.00007456053,0.02194544,0.00006052671,0.0003175954,0.00001158643,0.0001508181,0.0008231131,0.9546421,0.000001586065,0.001423143,0.01993883],"study_design_scores_gemma":[0.00133778,0.0001431081,0.05536477,0.0001960428,0.0002510007,0.00005339683,0.00008084192,0.00009126956,0.9392524,0.00002765457,0.002913517,0.0002881933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829655,0.01360958,0.000118555,0.001530053,0.0005959521,0.0003279523,0.0008275961,0.000005365789,0.00001941524],"genre_scores_gemma":[0.994589,0.002535004,0.0006861011,0.0006027256,0.001060896,0.0000410521,0.000009756507,0.00004321082,0.00043225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03341933,"threshold_uncertainty_score":0.7486141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006088135497452189,"score_gpt":0.2611353952044291,"score_spread":0.2550472597069769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}