{"id":"W2952644505","doi":"10.7150/jca.31241","title":"Exosomes from Macrophages Exposed to Apoptotic Breast Cancer Cells Promote Breast Cancer Proliferation and Metastasis","year":2019,"lang":"en","type":"article","venue":"Journal of Cancer","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; National Science Foundation","keywords":"Microvesicles; Metastasis; Cancer research; MMP2; Breast cancer; MMP9; STAT3; Exosome; Cancer cell; Apoptosis; Medicine; Cancer; Tumor microenvironment; Biology; Immunology; microRNA; Downregulation and upregulation; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000175672,0.0001532397,0.0002141641,0.0001886497,0.0001393885,0.0002514269,0.00005298582,0.0002121581,0.001126161],"category_scores_gemma":[0.000182263,0.00008102935,0.0002397378,0.00009014783,0.0001169424,0.0002685899,0.0002831862,0.0003149672,0.0003166316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009063837,"about_ca_system_score_gemma":0.0001539248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000154461,"about_ca_topic_score_gemma":0.0002155485,"domain_scores_codex":[0.9998735,0.00003397203,0.00001202755,0.00001525889,0.00002962144,0.00003547008],"domain_scores_gemma":[0.9999183,0.00002342652,0.00001268439,0.000008526573,0.00002184496,0.00001527268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003091605,0.00005589336,0.001179927,0.0001384314,0.00001341891,0.0002614671,0.00008825723,0.00004954008,0.9930433,0.000173775,0.0001309293,0.004555929],"study_design_scores_gemma":[0.0000505709,0.0007348416,0.02113918,0.00003842494,0.00003818082,0.0009391975,0.0002541028,0.0008801505,0.9665006,0.0002575664,0.009157588,0.000009548018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909575,0.00415673,0.002699221,0.0002630822,0.00007891504,0.00003810198,0.0002261956,0.00003078958,0.001549404],"genre_scores_gemma":[0.9932882,0.00217106,0.001787381,0.0001108953,0.00003964448,0.00003983641,0.0003070451,0.000009189666,0.002246748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001126161,"threshold_uncertainty_score":0.003767431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006088135497452189,"score_gpt":0.2611353952044291,"score_spread":0.2550472597069769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}