{"id":"W2952690147","doi":"10.1097/01.hs9.0000558800.37954.72","title":"S145 PHASE 3 RANDOMIZED STUDY OF DARATUMUMAB + BORTEZOMIB/THALIDOMIDE/DEXAMETHASONE (D-VTD) VERSUS VTD IN TRANSPLANT-ELIGIBLE NEWLY DIAGNOSED MULTIPLE MYELOMA: PART 1 CASSIOPEIA RESULTS","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Medicine; Daratumumab; Internal medicine; Multiple myeloma; Autologous stem-cell transplantation; Hazard ratio; Lenalidomide; Clinical endpoint; Thalidomide; Bortezomib; Surgery; Oncology; Gastroenterology; Randomized controlled trial; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001916996,0.001558552,0.002118704,0.0003422445,0.0003831678,0.001354066,0.0007329715,0.001217748,0.005631159],"category_scores_gemma":[0.001084995,0.0005835891,0.002126253,0.0003191026,0.0008377343,0.0006234759,0.0003555125,0.002880692,0.0009059609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009188631,"about_ca_system_score_gemma":0.001628828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009120574,"about_ca_topic_score_gemma":0.002957402,"domain_scores_codex":[0.9995074,0.0002724722,0.00002291346,0.00008141791,0.00004296655,0.00007276543],"domain_scores_gemma":[0.9991593,0.0001914506,0.0001980591,0.00005652538,0.00005325551,0.0003414187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9532967,0.01366908,0.001294774,0.00050659,0.00127335,0.00007131029,0.00007946941,0.0007841121,0.006832795,0.0002043808,0.002450208,0.01953706],"study_design_scores_gemma":[0.8821698,0.111462,0.003123672,0.00003181376,0.0004876989,0.00007486348,0.00002009826,0.0005765276,0.0006517763,0.0001869738,0.001196628,0.00001807899],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852642,0.004003445,0.0005676333,0.0006694136,0.0003779494,0.003916053,0.002072516,0.0001573944,0.002971379],"genre_scores_gemma":[0.9820322,0.002259866,0.001840438,0.001754279,0.0003746241,0.003784239,0.003664001,0.00004636827,0.004244023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005631159,"threshold_uncertainty_score":0.01883805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04402097614524465,"score_gpt":0.3431851252762097,"score_spread":0.2991641491309651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}