{"id":"W2952744187","doi":"10.1002/chin.200726060","title":"Asymmetric Syntheses of 1‐Aryl‐2,2,2‐trifluoroethylamines via Diastereoselective 1,2‐Addition of Arylmetals to 2‐Methyl‐N‐(2,2,2‐trifluoroethylidene)propane‐2‐sulfinamide.","year":2007,"lang":"en","type":"article","venue":"ChemInform","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Propane; Aryl; Combinatorial chemistry; Stereochemistry; Organic chemistry; Alkyl","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004137817,0.0007961759,0.0004863432,0.000372638,0.0004301403,0.0003634823,0.001162718,0.0006687061,0.003582707],"category_scores_gemma":[0.0003344102,0.0004073199,0.0004186117,0.0003339215,0.0002714669,0.0006672554,0.0005401151,0.001119046,0.002320435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000623656,"about_ca_system_score_gemma":0.0009568348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001296494,"about_ca_topic_score_gemma":0.005144714,"domain_scores_codex":[0.9997301,0.00003912356,0.00002524846,0.00004307419,0.00004724795,0.0001152404],"domain_scores_gemma":[0.9998876,0.00001860706,0.00003564882,0.00001510203,0.00001913895,0.000023881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004404656,0.0004013442,0.0002500539,0.001563775,0.0001163451,0.002239085,0.0007241229,0.001728997,0.9290794,0.008701181,0.008860653,0.04589472],"study_design_scores_gemma":[0.0001518532,0.0006463273,0.0008662952,0.00007257057,0.0000493386,0.00118155,0.00009677307,0.00190609,0.9551786,0.0008101594,0.03898258,0.00005782835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6871181,0.01835794,0.1485779,0.002234648,0.00226996,0.001386135,0.006622226,0.002035804,0.1313973],"genre_scores_gemma":[0.9295613,0.009423239,0.0367176,0.0003604489,0.0001477718,0.0003401296,0.001630108,0.0002039689,0.02161544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003582707,"threshold_uncertainty_score":0.01198536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06367037266514033,"score_gpt":0.3839882243668328,"score_spread":0.3203178517016925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}