{"id":"W2952810115","doi":"10.1093/cercor/bhy157","title":"Heritability of Regional Brain Volumes in Large-Scale Neuroimaging and Genetic Studies","year":2018,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Institute on Aging; National Institute of General Medical Sciences; National Institute of Mental Health; Medical Research Council; Canadian Institutes of Health Research; National Science Foundation; National Institutes of Health; Cancer Prevention and Research Institute of Texas","keywords":"Heritability; Biobank; Neurocognitive; Brain size; Neuroimaging; Single-nucleotide polymorphism; Brain Structure and Function; Biology; Genetics; Population; Genome-wide association study; Genetic correlation; Evolutionary biology; Genetic variation; Neuroscience; Medicine; Genotype; Magnetic resonance imaging; Cognition; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002291379,0.00009325854,0.0001939159,0.00002889686,0.00005331813,0.000003865221,0.00008091761,0.00007586962,0.00001252518],"category_scores_gemma":[0.0002719668,0.00008970012,0.00004104248,0.00007095557,0.0002754187,0.000002452272,0.0001297898,0.00005282796,0.000002208435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009419095,"about_ca_system_score_gemma":0.00003204166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003594837,"about_ca_topic_score_gemma":0.0005952371,"domain_scores_codex":[0.9990826,0.0001142474,0.0002460117,0.0002944653,0.0000526591,0.0002100305],"domain_scores_gemma":[0.9995412,0.000036297,0.00008423835,0.0001984069,0.0001017272,0.00003812195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00001909203,0.00003501386,0.9627399,0.00001698908,0.00002250789,7.140591e-7,0.0002311694,0.000003870105,0.03223846,0.00001878447,0.003060913,0.00161261],"study_design_scores_gemma":[0.0003535031,0.0001997454,0.9949533,0.000007513567,0.000007114377,0.000009461354,0.0004564004,0.0005592731,0.0007236073,0.0005745828,0.002063052,0.00009242249],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968961,0.001542873,0.0002529094,0.0009672235,0.0000842642,0.00009129199,0.00000935891,0.000004498036,0.0001514159],"genre_scores_gemma":[0.996689,0.0001486493,0.002214252,0.0005668144,0.0001263301,0.00000709038,0.00001323515,0.000008572568,0.0002260971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03221345,"threshold_uncertainty_score":0.3657865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02086853196600229,"score_gpt":0.2952834067639717,"score_spread":0.2744148747979694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}