{"id":"W2952838944","doi":"10.2174/2210303109666190617170026","title":"Systemic Delivery of Peptide Hormones Using Nasal Powders: Strategies and Future Perspectives","year":2019,"lang":"en","type":"article","venue":"Drug Delivery Letters","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Nasal administration; Hormone; Peptide hormone; Drug delivery; Ghrelin; Pharmacology; Internal medicine; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003262667,0.0005357407,0.001172305,0.001689773,0.0003486586,0.002226322,0.0008461947,0.002422964,0.004250262],"category_scores_gemma":[0.001957559,0.0002438424,0.001134645,0.0009500961,0.0008856425,0.00323287,0.0007275784,0.001704219,0.00123017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008377822,"about_ca_system_score_gemma":0.002193765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008439264,"about_ca_topic_score_gemma":0.001657309,"domain_scores_codex":[0.9992161,0.0002496124,0.0001046438,0.0001087035,0.0002614693,0.00005941062],"domain_scores_gemma":[0.9982882,0.0008777833,0.0002748948,0.00005024957,0.0004318051,0.00007707296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003656801,0.0002832258,0.0006322514,0.03743035,0.0001671391,0.0009738837,0.0002488362,0.0004306513,0.01333198,0.01221987,0.0181425,0.9157736],"study_design_scores_gemma":[0.0001370138,0.001307357,0.001646898,0.01098477,0.0003871203,0.003403184,0.0006586224,0.0007473914,0.007022221,0.009378167,0.9642374,0.00008984302],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008388133,0.9922875,0.0009483116,0.003783394,0.0003457915,0.00002996101,0.00003549898,0.00001618322,0.001714536],"genre_scores_gemma":[0.006556988,0.9886341,0.00196213,0.001427324,0.0005215379,0.00007562854,0.00005820759,0.000005879734,0.0007581656],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004250262,"threshold_uncertainty_score":0.01725483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03543976007651628,"score_gpt":0.3356558742412409,"score_spread":0.3002161141647247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}