{"id":"W2952865344","doi":"10.1016/j.jmb.2017.06.024","title":"ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain","year":2017,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"AP-1 transcription factor; Enhancer; Transcription factor; Biology; Activator (genetics); Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002173195,0.0001569805,0.0001738202,0.00004636778,0.0002677268,0.00006742962,0.0002828417,0.00009903284,0.00001056175],"category_scores_gemma":[0.0001473966,0.00009230716,0.0001179745,0.00001574881,0.0001319702,0.00001135744,0.00006781611,0.0002479623,6.645342e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002378905,"about_ca_system_score_gemma":0.00003650529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001773148,"about_ca_topic_score_gemma":0.0001647986,"domain_scores_codex":[0.9992893,0.00006658058,0.0002325557,0.0001680116,0.00007961493,0.000163942],"domain_scores_gemma":[0.9989868,0.00004837988,0.0004913444,0.000313901,0.00009607293,0.00006354058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000184918,0.00004964771,0.008486654,0.000005893638,0.0001991919,0.00000854574,0.0001741161,0.00005354877,0.9890921,0.0005097991,0.00003389771,0.001201762],"study_design_scores_gemma":[0.002810489,0.004037981,0.05637259,0.0002130566,0.000175695,0.0006960568,0.002605845,0.001046944,0.9165104,0.005000622,0.009908156,0.0006221611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865342,0.0001069742,0.01171856,0.001042045,0.0001954768,0.0001102107,0.00001071632,0.000002129784,0.0002797077],"genre_scores_gemma":[0.9983751,0.00007091758,0.001277908,0.0001194134,0.0001016821,0.000003437767,0.00001319721,0.00001740307,0.00002095342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07258163,"threshold_uncertainty_score":0.3764176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01658415515465287,"score_gpt":0.2763107274410778,"score_spread":0.2597265722864249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}