{"id":"W2952885191","doi":"10.1002/chin.200903248","title":"ChemInform Abstract: The Practice of Ring Constraint in Peptidomimetics Using Bicyclic and Polycyclic Amino Acids","year":2008,"lang":"en","type":"article","venue":"ChemInform","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Peptidomimetic; Ring (chemistry); Constraint (computer-aided design); Combinatorial chemistry; Bicyclic molecule; Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001550407,0.0007967906,0.0006266178,0.0008801071,0.0007586419,0.001609311,0.001067711,0.0005914335,0.02453974],"category_scores_gemma":[0.003017109,0.0004673443,0.0003626537,0.001393316,0.0005829831,0.001808576,0.00125986,0.001096605,0.008036631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005202983,"about_ca_system_score_gemma":0.001299081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006953815,"about_ca_topic_score_gemma":0.001257303,"domain_scores_codex":[0.9989873,0.0002365828,0.00008704657,0.0001575107,0.0004634298,0.00006817217],"domain_scores_gemma":[0.9991096,0.0003070162,0.0001299171,0.0002459967,0.0001234778,0.00008391117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001827455,0.0001753119,0.0006243367,0.002099602,0.0001210794,0.0007267202,0.0002451805,0.01387312,0.1915239,0.06187688,0.03646525,0.6904413],"study_design_scores_gemma":[0.0002972338,0.0009771219,0.0006293584,0.0003368779,0.0001145847,0.001500953,0.0001504551,0.04046666,0.4941287,0.02630199,0.4349462,0.0001498556],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.0804574,0.01867232,0.7498233,0.002407476,0.001667119,0.0008912527,0.004143048,0.01409381,0.1278443],"genre_scores_gemma":[0.3036026,0.01201664,0.6352538,0.0008749717,0.0003381504,0.000447513,0.003418897,0.002546173,0.04150117],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02453974,"threshold_uncertainty_score":0.0820936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531731170588954,"score_gpt":0.2555844188655013,"score_spread":0.2402671071596117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}