{"id":"W2952895316","doi":"10.1002/chin.200227183","title":"ChemInform Abstract: Stereocontrolled Synthesis of a Prototype Library of Enantiopure 2,4‐Disubstituted 4‐Aryl‐6‐piperidinones and Piperidines.","year":2002,"lang":"en","type":"article","venue":"ChemInform","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Enantiopure drug; Chemistry; Aryl; Combinatorial chemistry; Stereochemistry; Organic chemistry; Catalysis; Enantioselective synthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002378198,0.001115337,0.0004726278,0.0005398075,0.0002797078,0.0002676423,0.0008081059,0.000284307,0.01107782],"category_scores_gemma":[0.0001681846,0.0002948469,0.0003337456,0.0005329453,0.0002004874,0.0004301592,0.0002778664,0.0004794348,0.002952745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003818299,"about_ca_system_score_gemma":0.0007049224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001087696,"about_ca_topic_score_gemma":0.003035924,"domain_scores_codex":[0.9998744,0.00001220837,0.000008735637,0.00003183367,0.00002677352,0.00004606508],"domain_scores_gemma":[0.9999446,0.000006641753,0.000009989868,0.000007578511,0.00001062494,0.0000205276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009521485,0.0003648961,0.0002542202,0.001244731,0.00004309792,0.0009800036,0.0001518216,0.001770431,0.904508,0.001701094,0.006522765,0.08150683],"study_design_scores_gemma":[0.0004071402,0.005125861,0.00228928,0.00006901415,0.0001109033,0.001135977,0.00005400152,0.001165175,0.9363905,0.0003173758,0.05287277,0.00006209488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7903751,0.01301312,0.06076114,0.000672332,0.0006638885,0.001682032,0.02174433,0.003459049,0.107629],"genre_scores_gemma":[0.9146853,0.01143945,0.03316353,0.0003560606,0.00009266647,0.0003364956,0.009593894,0.0002207182,0.03011187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01107782,"threshold_uncertainty_score":0.03705901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04682928978316392,"score_gpt":0.3161339721660603,"score_spread":0.2693046823828963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}