{"id":"W2952913340","doi":"10.1097/01.hs9.0000562668.33884.40","title":"PS1094 MANAGING CYTOKINE RELEASE SYNDROME (CRS) AND NEUROTOXICITY WITH STEP‐FRACTIONATED DOSING OF MOSUNETUZUMAB IN RELAPSED/REFRACTORY (R/R) B‐CELL NON‐HODGKIN LYMPHOMA (NHL)","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Spinal Cord Injury BC; University of British Columbia","funders":"","keywords":"Medicine; Cytokine release syndrome; Adverse effect; Dosing; Gastroenterology; Internal medicine; Chills; Refractory (planetary science); Immunotherapy; Cancer; Chimeric antigen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000259694,0.0002181212,0.0003213661,0.0001348451,0.0001229535,0.0001729084,0.0002484657,0.0001825221,0.0007487097],"category_scores_gemma":[0.0003172196,0.00007362194,0.0001709923,0.0001269351,0.0001205113,0.0001558612,0.0001188561,0.0004720281,0.0001553663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002858919,"about_ca_system_score_gemma":0.0002583811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000526664,"about_ca_topic_score_gemma":0.001736932,"domain_scores_codex":[0.9999332,0.00002031293,0.000006541334,0.000009730613,0.0000146414,0.00001545913],"domain_scores_gemma":[0.9999161,0.00001904309,0.00002915788,0.0000097484,0.000006851579,0.00001914932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.03134385,0.007327652,0.03613081,0.0006949382,0.0005306205,0.000923907,0.0003781437,0.006022727,0.2368218,0.0001845887,0.002485812,0.6771551],"study_design_scores_gemma":[0.02946099,0.4176717,0.388898,0.0001735393,0.0008220452,0.007738165,0.0002156866,0.01061695,0.1319757,0.0004623947,0.01191305,0.00005174756],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9984511,0.0006538507,0.0002259559,0.00003417471,0.000004445029,0.00007759454,0.00004741848,0.00002373391,0.0004817247],"genre_scores_gemma":[0.9990706,0.0002929919,0.000265203,0.00003736979,0.000005900446,0.00003546201,0.00007995666,0.000002804724,0.0002097192],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.0007487097,"threshold_uncertainty_score":0.002504706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006455756891176972,"score_gpt":0.2172970572834731,"score_spread":0.2108413003922962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}