{"id":"W2952994283","doi":"10.1097/01.hs9.0000561608.73874.6a","title":"S832 A PHASE 2A STUDY OF THE LSD1 INHIBITOR IMG‐7289 FOR THE TREATMENT OF MYELOFIBROSIS","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Myelofibrosis; Ruxolitinib; Bone marrow; Myeloid; Internal medicine; Progenitor cell; Chronic myelomonocytic leukemia; Gastroenterology; Pharmacology; Oncology; Myelodysplastic syndromes; Immunology; Stem cell; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000633644,0.0007538314,0.001090905,0.0002924162,0.0002898448,0.0006726528,0.0005270427,0.0009205645,0.005524998],"category_scores_gemma":[0.0003248571,0.0003515859,0.0008860653,0.000238355,0.0003732867,0.0003898307,0.000198326,0.002322981,0.001084335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005506562,"about_ca_system_score_gemma":0.001046758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009623271,"about_ca_topic_score_gemma":0.002894351,"domain_scores_codex":[0.9998436,0.00005940928,0.000008769758,0.00003069728,0.00002299725,0.00003445968],"domain_scores_gemma":[0.9997928,0.00002247178,0.00004262938,0.00001547472,0.00002602462,0.0001006092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3962384,0.07445522,0.006850189,0.002156339,0.002291269,0.0009687593,0.0003595353,0.005517501,0.2423823,0.0009792282,0.02425796,0.2435433],"study_design_scores_gemma":[0.3838318,0.549635,0.01967768,0.0001434489,0.0009104328,0.001629474,0.0001084063,0.00402552,0.02342458,0.000511244,0.01603323,0.00006932059],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865346,0.003186208,0.0009161527,0.0009053246,0.0001701674,0.002245949,0.002976367,0.0002155379,0.002849621],"genre_scores_gemma":[0.9833547,0.002305961,0.002513667,0.001393376,0.0001012752,0.001683673,0.004047188,0.00004506193,0.004555032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005524998,"threshold_uncertainty_score":0.01848292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02639573131401898,"score_gpt":0.3162784913377868,"score_spread":0.2898827600237678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}