{"id":"W2953041939","doi":"10.82308/54464","title":"Reciprocal regulation of DNA binding of the paired domain and homedomain of Pax3","year":2006,"lang":"en","type":"article","venue":"eScholarship@McGill (McGill)","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; McGill University","keywords":"PAX3; Mutant; DNA; Binding site; DNA-binding domain; Chemistry; Transcription factor; Biology; Genetics; Molecular biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001267561,0.0003136685,0.0001477857,0.0001375805,0.0001556782,0.0002130847,0.0002071271,0.0001896885,0.001993098],"category_scores_gemma":[0.0001692571,0.0001700119,0.0002088538,0.0000852441,0.0003223769,0.0001740549,0.0005051233,0.0004853991,0.0003956312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003295936,"about_ca_system_score_gemma":0.0001217643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000278687,"about_ca_topic_score_gemma":0.0005831848,"domain_scores_codex":[0.9997686,0.00004027267,0.00001446991,0.00005930757,0.00006842704,0.00004905146],"domain_scores_gemma":[0.9998478,0.0000443829,0.00004058841,0.00001800781,0.00001665486,0.00003254275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000031415,0.000003501742,0.00009580325,0.000007912095,0.000001551306,0.00001931511,0.000004465242,0.00002603019,0.9993728,0.00009808667,0.000006866999,0.0003323487],"study_design_scores_gemma":[0.000008432332,0.00005000861,0.00366075,0.000002503788,0.000004731012,0.0001837772,0.00001855498,0.00070062,0.9944747,0.00008791511,0.0008055532,0.000002469561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953611,0.0006234577,0.002749925,0.00004222042,0.00001794339,0.000008595614,0.0001081935,0.00004518911,0.001043515],"genre_scores_gemma":[0.9979608,0.00009969417,0.0008500319,0.00001901258,0.000002285912,0.00001035917,0.0001116653,0.00001089864,0.0009352028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001993098,"threshold_uncertainty_score":0.006667554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006822456684168363,"score_gpt":0.1838886274755728,"score_spread":0.1770661707914044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}