{"id":"W2953073283","doi":"10.3389/fimmu.2019.01414","title":"What Defines NK Cell Functional Fate: Phenotype or Metabolism?","year":2019,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":139,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"Ontario Ministry of Health and Long-Term Care; Canadian Institutes of Health Research; Government of Ontario","keywords":"Biology; Cell biology; Effector; Phenotype; Cell metabolism; Cell; Immune system; Cell fate determination; Natural killer cell; Cell type; Cytotoxic T cell; Immunology; Transcription factor; In vitro; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001039826,0.0003209062,0.001541998,0.000750053,0.0002542773,0.002297729,0.0005209749,0.001031351,0.001423543],"category_scores_gemma":[0.00232008,0.0002174155,0.0004064635,0.0008567451,0.001830316,0.00302484,0.0004913405,0.001159703,0.0007894894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006930112,"about_ca_system_score_gemma":0.0006731293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001206523,"about_ca_topic_score_gemma":0.001189134,"domain_scores_codex":[0.9994873,0.0001545872,0.0000593052,0.000145735,0.0000920848,0.00006087681],"domain_scores_gemma":[0.9991565,0.000309861,0.0001650277,0.00006493058,0.0002185899,0.00008504657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001163764,0.000137378,0.05170876,0.0100467,0.0004502779,0.00123391,0.002092979,0.001502886,0.1336124,0.05045018,0.02083831,0.7267625],"study_design_scores_gemma":[0.00009361908,0.000841714,0.1668191,0.007112099,0.0008890102,0.01247027,0.0100147,0.004789202,0.08305891,0.1190174,0.5944881,0.0004057621],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1193653,0.7885943,0.03720048,0.02978518,0.003000414,0.0001113946,0.001971534,0.0001963502,0.01977513],"genre_scores_gemma":[0.4331797,0.5338735,0.0131072,0.008307579,0.002935395,0.0001783397,0.001158932,0.0001655994,0.007093841],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002297729,"threshold_uncertainty_score":0.005499244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03133732639658086,"score_gpt":0.2626531814844011,"score_spread":0.2313158550878203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}