{"id":"W2953093055","doi":"10.1101/668277","title":"The Eya1 phosphatase mediates Shh-driven symmetric cell division of cerebellar granule cell precursors","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institutes of Health; Deutsche Krebshilfe; Deutsche Forschungsgemeinschaft","keywords":"Cell biology; Asymmetric cell division; Spindle apparatus; Cell division; Sonic hedgehog; Mitosis; Biology; Multipolar spindles; Granule cell; Cell polarity; Cell fate determination; Signal transduction; Cell; Neuroscience; Hippocampal formation; Transcription factor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008598482,0.0007214143,0.000698232,0.0002030101,0.000280446,0.0001125241,0.001252832,0.000753027,0.000009971483],"category_scores_gemma":[0.0004399878,0.0006124128,0.0003520692,0.0004923881,0.0002822658,0.000008713359,0.001517379,0.0005869874,0.00007292616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008043847,"about_ca_system_score_gemma":0.0005438058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004818679,"about_ca_topic_score_gemma":0.000003749678,"domain_scores_codex":[0.9964566,0.0002594207,0.000762748,0.001232072,0.0005585943,0.0007305166],"domain_scores_gemma":[0.9960318,0.0001818007,0.0008265261,0.002080046,0.0006506192,0.000229233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006021175,0.0002395667,0.01180888,0.0007779159,0.0002135248,0.00001010967,0.00002031361,0.0009364229,0.9839947,0.0000442051,0.001888793,0.000005344622],"study_design_scores_gemma":[0.0006589141,0.0002208133,0.00781547,0.0001669409,0.0001538259,5.729261e-9,0.00001140963,0.0002476012,0.9774893,0.000001428946,0.01255283,0.0006814923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9568782,0.03870909,0.0006203848,0.00006071142,0.001618656,0.001085221,0.0009005567,0.00007607013,0.00005110038],"genre_scores_gemma":[0.9928847,0.005582288,0.0008204396,0.00006207237,0.0003287859,0.000115643,0.000007506881,0.0001617482,0.0000367915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03600651,"threshold_uncertainty_score":0.9996327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008466052356620459,"score_gpt":0.2069266708086553,"score_spread":0.1984606184520348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}