{"id":"W2953103085","doi":"10.1002/chin.200042130","title":"ChemInform Abstract: Design and Evaluation of Dihydroisoquinolines as Potent and Orally Bioavailable Human Cytomegalovirus Inhibitors.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BioPhage Pharma (Canada)","funders":"","keywords":"Chemistry; Bioavailability; Combinatorial chemistry; Orally active; Service (business); Pharmacology; Biochemistry; Business; Marketing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003498934,0.0006916971,0.0004779422,0.0004927269,0.0001754112,0.0005454451,0.0006382026,0.0004324086,0.004075445],"category_scores_gemma":[0.0001851955,0.0002553227,0.0003039423,0.000279171,0.0001923683,0.0003775397,0.0002453398,0.0006405846,0.001253871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005394233,"about_ca_system_score_gemma":0.0006369706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001281613,"about_ca_topic_score_gemma":0.003201184,"domain_scores_codex":[0.9998984,0.00002139314,0.000006190367,0.00001691695,0.00002862795,0.00002844019],"domain_scores_gemma":[0.999946,0.000006392489,0.00001172391,0.000003356768,0.00001109205,0.0000215228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004696213,0.001338779,0.0006212755,0.001448105,0.000155041,0.0006293718,0.000173809,0.004890538,0.7335392,0.004588057,0.01754592,0.2303737],"study_design_scores_gemma":[0.007949128,0.02611763,0.003796805,0.0002083647,0.0005435134,0.002093784,0.0000854465,0.005619259,0.7735552,0.001277005,0.178637,0.0001169263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7673402,0.1127552,0.03937817,0.002199761,0.001208896,0.002490032,0.01153102,0.002047032,0.06104983],"genre_scores_gemma":[0.891791,0.04860706,0.01606853,0.001068251,0.0001874026,0.0004606986,0.009515533,0.0001310838,0.03217042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004075445,"threshold_uncertainty_score":0.01363367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02948570802194561,"score_gpt":0.2621737869870835,"score_spread":0.2326880789651379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}