{"id":"W2953140920","doi":"10.1002/chin.200633157","title":"Studies on Cu‐Catalyzed Asymmetric Alkynylation of Tetrahydroisoquinoline Derivatives.","year":2006,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and Biological Activity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Chemistry; Alkynylation; Tetrahydroisoquinoline; Catalysis; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000511428,0.0005157426,0.0004302262,0.0001764407,0.0003200724,0.000223262,0.0006112537,0.0004128135,0.002680478],"category_scores_gemma":[0.0004917101,0.0001520233,0.0002704982,0.0002922718,0.0003035164,0.000542888,0.0002924858,0.000716737,0.0007740787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005615317,"about_ca_system_score_gemma":0.0004208327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002785548,"about_ca_topic_score_gemma":0.003222199,"domain_scores_codex":[0.9996306,0.0000893082,0.00002201201,0.00005209838,0.00006271351,0.0001432697],"domain_scores_gemma":[0.999855,0.00003670779,0.00003377615,0.00001871515,0.00003365015,0.0000222228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000973207,0.0004073509,0.0002242635,0.001011831,0.000125112,0.0006620446,0.0006558095,0.00199826,0.9719364,0.002405735,0.001956284,0.01764361],"study_design_scores_gemma":[0.0001390801,0.00180617,0.0006715289,0.00003100614,0.00005991491,0.0005084963,0.000125501,0.001280839,0.9824364,0.0002932744,0.01260709,0.0000405434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9578895,0.01076554,0.007925139,0.0003590005,0.0002343274,0.0002486702,0.0004100418,0.0001395282,0.02202825],"genre_scores_gemma":[0.9897238,0.004202835,0.00163644,0.00006273398,0.00002127839,0.00003265325,0.0002515942,0.00002831131,0.004040484],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002785548,"threshold_uncertainty_score":0.008967102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02173068279751083,"score_gpt":0.2678494698428647,"score_spread":0.2461187870453539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}