{"id":"W2953217540","doi":"10.1002/chin.201210127","title":"ChemInform Abstract: Substituted Phenyl 4‐(2‐Oxoimidazolidin‐1‐yl)benzenesulfonamides as Antimitotics. Antiproliferative, Antiangiogenic and Antitumoral Activity, and Quantitative Structure—Activity Relationships.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Enzyme function and inhibition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Saint-François d'Assise","funders":"","keywords":"Chemistry; Stereochemistry; Combinatorial chemistry; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002362171,0.0006175711,0.0002525614,0.0003486607,0.000128086,0.0001590588,0.0003302462,0.0001874879,0.005563149],"category_scores_gemma":[0.0001345025,0.0001987549,0.0001251941,0.000307296,0.0001781784,0.0001857783,0.0001458435,0.000297565,0.001186854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005109339,"about_ca_system_score_gemma":0.000544171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001229082,"about_ca_topic_score_gemma":0.003002605,"domain_scores_codex":[0.9999084,0.000017136,0.000004756344,0.00001082865,0.00004028837,0.0000185098],"domain_scores_gemma":[0.9999428,0.000008452877,0.00001835037,0.000003602666,0.00001381644,0.0000129189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001097643,0.0002277778,0.0005809757,0.0005762206,0.0000390539,0.0001545086,0.00004750645,0.001111836,0.9605286,0.001660254,0.003030839,0.03094491],"study_design_scores_gemma":[0.0003263924,0.001823185,0.003420729,0.00003024394,0.00007119643,0.0002782792,0.00001946746,0.001395819,0.9712385,0.0001119652,0.0212653,0.00001893912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8947315,0.03398281,0.0169759,0.0008490432,0.0002131269,0.0002823653,0.005217633,0.001332926,0.04641476],"genre_scores_gemma":[0.9499683,0.01655286,0.00934,0.0002321272,0.0000423713,0.0001276217,0.004178947,0.00003802151,0.01951968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005563149,"threshold_uncertainty_score":0.01861054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02541318254971999,"score_gpt":0.2664224850098815,"score_spread":0.2410093024601615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}