{"id":"W2953217540","doi":"10.1002/chin.201210127","title":"ChemInform Abstract: Substituted Phenyl 4‐(2‐Oxoimidazolidin‐1‐yl)benzenesulfonamides as Antimitotics. Antiproliferative, Antiangiogenic and Antitumoral Activity, and Quantitative Structure—Activity Relationships.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Enzyme function and inhibition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Saint-François d'Assise","funders":"","keywords":"Chemistry; Stereochemistry; Combinatorial chemistry; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002750995,0.0003828586,0.0003079942,0.0001145429,0.000357686,0.0001115414,0.0001070129,0.000363759,0.0001339843],"category_scores_gemma":[0.0003246475,0.0003723202,0.0001018465,0.0001959848,0.0003012864,0.0002185041,0.0001567049,0.0003108384,0.00001698166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004063664,"about_ca_system_score_gemma":0.00009488793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004073067,"about_ca_topic_score_gemma":0.00004369721,"domain_scores_codex":[0.9985686,0.000001812227,0.0003019288,0.0003953484,0.0002356766,0.0004966252],"domain_scores_gemma":[0.9989566,0.00004745152,0.0002543289,0.0003055201,0.0001533746,0.0002827859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004365657,0.0001526325,0.01525504,0.0001538446,0.0001580881,0.000003338191,0.000562798,0.000001511229,0.9595354,0.002038712,0.004356725,0.01734541],"study_design_scores_gemma":[0.0007802779,0.0001025255,0.1207065,0.0000356306,0.00005289674,0.0001245546,0.0002347194,0.00005191115,0.8741266,0.00008254483,0.003252103,0.0004498243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9560837,0.0007142585,0.00002082113,0.00009999929,0.0003035943,0.0002953396,0.00008509365,0.00004925115,0.042348],"genre_scores_gemma":[0.9971995,0.0004209898,0.0001923417,0.0001120596,0.0002872783,0.0000131651,0.0003071372,0.00003385552,0.001433709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1054514,"threshold_uncertainty_score":0.9998729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02541318254971999,"score_gpt":0.2664224850098815,"score_spread":0.2410093024601615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}