{"id":"W2953253538","doi":"10.1021/ol8014682","title":"Ring Expansion of Lactones and Lactams via Propiolate 1-Carbon Intercalation","year":2008,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Cycloisomerization; Pyridinium; Ring (chemistry); Nucleophile; Catalysis; Adduct; Intercalation (chemistry); Medicinal chemistry; Carbon fibers; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001224699,0.0001694722,0.0002288132,0.00003230834,0.00004968564,0.000007684414,0.0001314608,0.0001143133,0.0004993642],"category_scores_gemma":[0.0001042666,0.0001635594,0.00004122049,0.0001055751,0.0001219294,0.00006758451,0.00009279684,0.0001783633,0.000005111354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007509242,"about_ca_system_score_gemma":0.00002614483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002957977,"about_ca_topic_score_gemma":8.054111e-7,"domain_scores_codex":[0.999023,0.00002195413,0.0002874633,0.0002868844,0.0001880483,0.0001926937],"domain_scores_gemma":[0.9993429,0.00009209519,0.0001453752,0.0003284139,0.00002527913,0.00006590279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001808909,0.00001840254,0.006465632,0.0001205533,0.00002225773,0.00001133944,0.0006896707,6.946001e-7,0.9902306,0.000001378607,0.00001735645,0.002403984],"study_design_scores_gemma":[0.00040409,0.000007593602,0.001851654,0.00007991239,0.00002500489,0.0001637527,0.00006071609,0.0004402562,0.9967181,0.00001784653,0.00006222061,0.0001688236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972591,0.00004754278,0.0009520904,0.0005199261,0.00007536151,0.00004430365,0.000001226838,0.0000856398,0.001014852],"genre_scores_gemma":[0.9980674,0.00004138098,0.001580221,0.00007871466,0.0001151503,0.000002881064,0.000004178001,0.00004139599,0.00006870221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006487487,"threshold_uncertainty_score":0.6669759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01465834171249297,"score_gpt":0.229789731386508,"score_spread":0.215131389674015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}