{"id":"W2953261057","doi":"10.1152/ajpgi.00104.2019","title":"NTPDase1 and -2 are expressed by distinct cellular compartments in the mouse colon and differentially impact colonic physiology and function after DSS colitis","year":2019,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Institute of Health Services and Policy Research; National Institute of Diabetes and Digestive and Kidney Diseases; Leona M. and Harry B. Helmsley Charitable Trust; Canadian Institutes of Health Research; Government of Canada; Crohn's and Colitis Foundation; Crohn's and Colitis Canada","keywords":"Extracellular; Motility; Cell biology; Biology; Nucleoside triphosphate; Enteric nervous system; Myenteric plexus; Purinergic receptor; Inflammation; Immunology; Neuroscience; Biochemistry; Nucleotide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002010847,0.0006823325,0.0004058157,0.00104056,0.0002434004,0.0005185671,0.0003206961,0.0007578954,0.002092338],"category_scores_gemma":[0.0001520058,0.0005732127,0.0004887322,0.0004523105,0.0006032184,0.0005454846,0.0003571804,0.001267329,0.0005280069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004382897,"about_ca_system_score_gemma":0.0002256798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007564104,"about_ca_topic_score_gemma":0.001693555,"domain_scores_codex":[0.9995096,0.00003869899,0.00005412071,0.0001679607,0.0001127815,0.0001168692],"domain_scores_gemma":[0.999556,0.00003372287,0.0001884367,0.00003255131,0.00002411837,0.0001652916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003605439,0.00003212691,0.0004430847,0.00002692449,0.000005182317,0.00008917218,0.0000252781,0.00003144668,0.998406,0.00006683599,0.00002203183,0.0004914218],"study_design_scores_gemma":[0.0001135029,0.0009172798,0.04187208,0.00002715753,0.00008623347,0.001728603,0.0002245022,0.001316506,0.9499408,0.0001820298,0.003568381,0.00002297423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937239,0.001645373,0.002453658,0.0001448678,0.00003826188,0.00002868044,0.001030835,0.0001048448,0.000829459],"genre_scores_gemma":[0.983825,0.001582264,0.003822926,0.0001583976,0.00002136087,0.0001601838,0.001684405,0.0001051188,0.008640403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002092338,"threshold_uncertainty_score":0.006999552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004259966544864225,"score_gpt":0.2078836848951513,"score_spread":0.2036237183502871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}