{"id":"W2953296556","doi":"10.1167/tvst.8.3.43","title":"Subretinal Transplantation of Human Central Nervous System Stem Cells Stimulates Controlled Proliferation of Endogenous Retinal Pigment Epithelium","year":2019,"lang":"en","type":"article","venue":"Translational Vision Science & Technology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; McGill University; Research to Prevent Blindness","keywords":"Retinitis pigmentosa; Transplantation; Retinal pigment epithelium; Stem cell; Bromodeoxyuridine; Retinal; Retinal degeneration; Biology; RPE65; Retinal regeneration; Pathology; Regeneration (biology); Macular degeneration; Cell biology; Medicine; Internal medicine; Ophthalmology; Immunohistochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005297263,0.000158114,0.000308612,0.0003765204,0.0001264041,0.00001429722,0.0003217874,0.0001557401,0.00002367419],"category_scores_gemma":[0.000008027653,0.0001386347,0.00009638102,0.0004620426,0.000410471,0.00002073676,0.00002352152,0.00007799769,0.000005788115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002272017,"about_ca_system_score_gemma":0.0002136509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007206158,"about_ca_topic_score_gemma":0.000004173798,"domain_scores_codex":[0.998161,0.00005018303,0.0005976089,0.000397168,0.0005077622,0.0002862866],"domain_scores_gemma":[0.9991172,0.000023247,0.0002819008,0.0002158588,0.000312398,0.00004941896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007544272,0.00007599936,0.0189356,0.0001162144,0.00001647259,0.000001344799,0.0001405589,0.001901684,0.9732062,0.003619008,0.000002071954,0.00123039],"study_design_scores_gemma":[0.002937701,0.0009999871,0.01248599,0.00007055674,0.00003162404,0.00002954176,0.000266435,0.001817618,0.9809888,0.0001653882,0.00004322589,0.0001631071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928773,0.000174413,0.00501426,0.0001211481,0.0001141671,0.0008835359,0.00002141921,0.0000257732,0.0007679588],"genre_scores_gemma":[0.9990591,0.0000309772,0.0007499449,0.000009222892,0.0000150948,0.00002742887,0.00005251973,0.000009813005,0.00004587475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007782592,"threshold_uncertainty_score":0.5653359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009572935588516657,"score_gpt":0.2526448024379512,"score_spread":0.2430718668494346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}