{"id":"W2953296556","doi":"10.1167/tvst.8.3.43","title":"Subretinal Transplantation of Human Central Nervous System Stem Cells Stimulates Controlled Proliferation of Endogenous Retinal Pigment Epithelium","year":2019,"lang":"en","type":"article","venue":"Translational Vision Science & Technology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; McGill University; Research to Prevent Blindness","keywords":"Retinitis pigmentosa; Transplantation; Retinal pigment epithelium; Stem cell; Bromodeoxyuridine; Retinal; Retinal degeneration; Biology; RPE65; Retinal regeneration; Pathology; Regeneration (biology); Macular degeneration; Cell biology; Medicine; Internal medicine; Ophthalmology; Immunohistochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001454673,0.0003705001,0.0002507138,0.0003903848,0.00009909894,0.0001944004,0.0001594054,0.0002176013,0.001471275],"category_scores_gemma":[0.000122208,0.0000895123,0.0002285014,0.0001652418,0.0002619832,0.0001560261,0.0001843133,0.000455241,0.0003166195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001851484,"about_ca_system_score_gemma":0.0002226538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005690742,"about_ca_topic_score_gemma":0.00121379,"domain_scores_codex":[0.9998634,0.00001358244,0.00001311281,0.00002728705,0.00005358557,0.00002902993],"domain_scores_gemma":[0.9998381,0.00003035163,0.00005762552,0.00002140516,0.00001638885,0.00003606856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001911817,0.0001286901,0.0004482209,0.00003865563,0.000005524722,0.00007316866,0.00001977002,0.00005769061,0.9962723,0.00002935587,0.00004003394,0.002695249],"study_design_scores_gemma":[0.00004928655,0.002482618,0.009192551,0.00001523424,0.00003716939,0.0003488126,0.00005453797,0.0007013956,0.9858605,0.00002210437,0.001231885,0.000003931743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984121,0.0004549494,0.0004051039,0.00001485808,0.00001022279,0.00001765218,0.00006136864,0.0000391231,0.0005845879],"genre_scores_gemma":[0.9965214,0.0006423293,0.001171194,0.00001723269,0.00001010549,0.00002925509,0.0002140563,0.000009754956,0.001384705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001471275,"threshold_uncertainty_score":0.004921913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009572935588516657,"score_gpt":0.2526448024379512,"score_spread":0.2430718668494346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}