{"id":"W2953360717","doi":"10.1021/ol702933g","title":"An Efficient Three-Component One-Pot Approach to the Synthesis of 2,3,4,5-Tetrahydro-1<i>H</i>-2-benzazepines by Means of Rhodium-Catalyzed Hydroaminomethylation","year":2008,"lang":"en","type":"article","venue":"Organic Letters","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Benzazepines; Rhodium; Chemistry; Catalysis; Component (thermodynamics); Phosphine; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003695353,0.0002673829,0.0004706687,0.0002434223,0.0001654236,0.00001606302,0.000749236,0.0001124021,0.000289644],"category_scores_gemma":[0.0001898833,0.0002202022,0.0001982123,0.001213617,0.0001617105,0.00008820347,0.00007854615,0.0001595364,0.00003694819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001326222,"about_ca_system_score_gemma":0.00004467943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000156762,"about_ca_topic_score_gemma":0.000008205688,"domain_scores_codex":[0.9976953,0.00007021157,0.0006498997,0.0004799661,0.00079047,0.0003141013],"domain_scores_gemma":[0.9982315,0.0002238115,0.0003633193,0.0009398726,0.00008868907,0.0001528328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002544512,0.0006295051,0.0006379765,0.00006787152,0.0001783531,0.000001044646,0.001064925,0.002967217,0.9922535,0.0000257849,0.0005803106,0.001568046],"study_design_scores_gemma":[0.0003644378,0.00001212767,0.0008996071,0.00001719202,0.0001448433,0.000009381148,0.0002080117,0.009216329,0.9886688,0.000002515342,0.0001984001,0.00025838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765253,0.0001220603,0.02053558,0.00102691,0.00004553661,0.0001919778,0.00008812307,0.000068416,0.001396082],"genre_scores_gemma":[0.9985831,0.00001534412,0.0007891442,0.0002401882,0.00007376281,0.00004115795,0.0001825995,0.00004922061,0.00002545719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02205781,"threshold_uncertainty_score":0.8979584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01397623460962503,"score_gpt":0.2042192667028243,"score_spread":0.1902430320931993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}