{"id":"W2953400167","doi":"10.1016/j.devcel.2019.06.006","title":"Repressive Epigenetic Signatures Safeguard the Liver","year":2019,"lang":"en","type":"letter","venue":"Developmental Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Terry Fox Research Institute; University of British Columbia","funders":"","keywords":"Biology; Epigenetics; Safeguard; Computational biology; Genetics; Gene; International trade","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001673602,0.0003760844,0.0002263987,0.00005390591,0.0001414178,0.00005833598,0.0005300206,0.0009220259,0.0003459683],"category_scores_gemma":[0.00003680662,0.0002861854,0.0001674416,0.00007383928,0.0001176836,0.000002144892,0.0003165822,0.000710376,0.0006598662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000448393,"about_ca_system_score_gemma":0.000219032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001857964,"about_ca_topic_score_gemma":0.000007779694,"domain_scores_codex":[0.9981462,0.0001487141,0.000306738,0.0006738495,0.0003366254,0.0003879265],"domain_scores_gemma":[0.9990467,0.00006111477,0.0002197104,0.0005480016,0.00008979994,0.00003470663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002244031,0.00001751842,0.0001213435,0.0000839577,0.00007980759,0.00004817254,0.0001110242,0.00005810252,0.08540332,7.724026e-7,0.9119618,0.002091733],"study_design_scores_gemma":[0.0001633367,0.00007780963,0.000455727,0.00001645508,0.00002713714,0.000004162961,0.00002079104,0.00000528199,0.2522201,0.00002155175,0.7466507,0.000336943],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.2186663,0.213067,0.002121566,0.174429,0.007151611,0.007506928,0.0007909594,0.0001764764,0.3760902],"genre_scores_gemma":[0.1551572,0.007452744,0.003988067,0.5719688,0.007872012,0.0002240738,0.009468529,0.0003945994,0.243474],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.3975399,"threshold_uncertainty_score":0.9999591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009957919320141976,"score_gpt":0.2090822023884589,"score_spread":0.1991242830683169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}