{"id":"W2953470384","doi":"10.2210/pdb6no1/pdb","title":"ADP bound to K46bE mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase","year":2019,"lang":"en","type":"paratext","venue":"","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Nucleotide; Linker; GTP'; Stereochemistry; Binding site; Active site; Chemistry; Biochemistry; Adenine nucleotide; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003681476,0.0006174627,0.001127066,0.0003084136,0.000129185,0.0001673732,0.0006569016,0.0005834213,0.04041938],"category_scores_gemma":[0.0001096758,0.0004893171,0.0002756478,0.0003211336,0.0001317272,0.0001853926,0.0002610282,0.0002954484,0.03203852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001264674,"about_ca_system_score_gemma":0.0003188625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086864,"about_ca_topic_score_gemma":0.0004551217,"domain_scores_codex":[0.9967543,0.000112032,0.0008256758,0.0009971921,0.0006675773,0.0006431917],"domain_scores_gemma":[0.9976599,0.0002195545,0.0004757475,0.001170099,0.0002261179,0.000248573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002435111,0.00004738097,0.000009607872,0.0003242261,0.00005676199,0.00001083161,0.0002463725,0.000255199,0.6067879,0.000302343,0.3912744,0.0004414955],"study_design_scores_gemma":[0.000422155,0.0005651801,0.00008128766,0.0002410871,0.0001286422,0.00003723582,0.00009503344,0.00001950125,0.6289479,0.00005916945,0.3687685,0.0006343503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4932089,0.00142837,0.008973914,0.0006866347,0.04662077,0.00340129,0.004160214,0.0002815484,0.4412384],"genre_scores_gemma":[0.617185,0.0001123133,0.001509995,0.0009297067,0.001391844,0.00009837825,0.0003079556,0.0001645336,0.3783002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1239761,"threshold_uncertainty_score":0.9997559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01041513417916271,"score_gpt":0.2466032287466855,"score_spread":0.2361880945675228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}