{"id":"W2953508770","doi":"10.1002/etc.4531","title":"Mode of Action Classifications in the EnviroTox Database: Development and Implementation of a Consensus MOA Classification","year":2019,"lang":"en","type":"article","venue":"Environmental Toxicology and Chemistry","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Environment and Climate Change Canada","funders":"Environment and Climate Change Canada; Natural Environment Research Council; Sight Research UK; Health and Environmental Sciences Institute; U.S. Environmental Protection Agency","keywords":"Mode of action; Mode (computer interface); Computer science; Database; Biology; Toxicology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02191412,0.002370363,0.00296044,0.01738966,0.001949303,0.005826842,0.005165383,0.002118309,0.004910324],"category_scores_gemma":[0.04567681,0.001571929,0.004243541,0.007866131,0.0009588526,0.005678757,0.005248746,0.003371962,0.004600783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002886547,"about_ca_system_score_gemma":0.008063906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009451604,"about_ca_topic_score_gemma":0.009787587,"domain_scores_codex":[0.9865407,0.001843422,0.004168823,0.002336887,0.004521849,0.0005881598],"domain_scores_gemma":[0.9697687,0.00791561,0.004089731,0.005763987,0.01148577,0.0009761365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003007665,0.001433659,0.0719441,0.008629527,0.001647969,0.001643436,0.003575473,0.03485768,0.03131038,0.03349116,0.165475,0.6429841],"study_design_scores_gemma":[0.0007216696,0.0009751366,0.04031225,0.003104711,0.001322232,0.001360751,0.001592492,0.2413785,0.05948711,0.05087422,0.5979279,0.0009431026],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.06012733,0.001997187,0.652994,0.001514855,0.0004965691,0.005856781,0.142463,0.1163321,0.01821826],"genre_scores_gemma":[0.0462338,0.0007832491,0.781637,0.0004374092,0.00005975167,0.00318166,0.1608895,0.004335248,0.002442436],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.02191412,"threshold_uncertainty_score":0.1158944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02915026387392632,"score_gpt":0.3204837890398717,"score_spread":0.2913335251659454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}