{"id":"W2953613982","doi":"10.1038/s41393-019-0309-x","title":"Guidelines for the conduct of clinical trials in spinal cord injury: Neuroimaging biomarkers","year":2019,"lang":"en","type":"review","venue":"Spinal Cord","topic":"Spinal Cord Injury Research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; European Commission; Wellcome Trust; Multiple Sclerosis Society; National Institute for Health and Care Research; University College London; Craig H. Neilsen Foundation; National Science Foundation","keywords":"Medicine; Neuroimaging; Neuroprotection; Spinal cord injury; Neuroscience; Clinical trial; Spinal cord; Pathology; Internal medicine; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.09399253,0.002805949,0.007595619,0.00622345,0.001686772,0.006519957,0.008573561,0.01812379,0.01346378],"category_scores_gemma":[0.1589295,0.002105454,0.008706325,0.006847762,0.003523234,0.004631898,0.003008655,0.0105682,0.01450108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003911423,"about_ca_system_score_gemma":0.02812674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00370259,"about_ca_topic_score_gemma":0.005948184,"domain_scores_codex":[0.8922883,0.05884849,0.03102215,0.002698505,0.01358896,0.001553688],"domain_scores_gemma":[0.7638431,0.1498859,0.02371531,0.007697524,0.05110406,0.003754197],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001083598,0.0001932901,0.0004353391,0.1602573,0.001097267,0.0005408059,0.0005698539,0.0009130344,0.001485504,0.01786752,0.2824949,0.5330615],"study_design_scores_gemma":[0.001314879,0.0002363595,0.00155992,0.2097225,0.002164152,0.0004951296,0.0002016544,0.0004995976,0.0007266829,0.01835631,0.7645945,0.0001283453],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.0007050816,0.7469392,0.05687896,0.09771982,0.01926341,0.03187884,0.008316124,0.001910851,0.03638767],"genre_scores_gemma":[0.007561885,0.5222229,0.3065077,0.06138053,0.006535297,0.07478788,0.008094464,0.0006104166,0.01229904],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.9060075,"threshold_uncertainty_score":0.4970859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8463697277035203,"score_gpt":0.6927921622795358,"score_spread":0.1535775654239845,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}