{"id":"W2953671548","doi":"10.4049/jimmunol.1801472","title":"LILRB1 Blockade Enhances Bispecific T Cell Engager Antibody–Induced Tumor Cell Killing by Effector CD8+ T Cells","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"U.S. Food and Drug Administration; Amgen","keywords":"Effector; Blockade; Cytotoxic T cell; Bispecific antibody; T cell; CD8; Antibody; Cell biology; Cancer research; Cell; Chemistry; Molecular biology; Biology; Antigen; Immunology; Biochemistry; Receptor; Monoclonal antibody; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001927191,0.000640966,0.0004971678,0.000265619,0.0001055409,0.000311537,0.0002003034,0.0003851241,0.001812783],"category_scores_gemma":[0.0001378627,0.0001319129,0.0002352919,0.0001374993,0.0001578561,0.000206053,0.0002336559,0.001285542,0.0006404629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002184173,"about_ca_system_score_gemma":0.000155507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001732662,"about_ca_topic_score_gemma":0.000294904,"domain_scores_codex":[0.9996502,0.00007473792,0.00003336439,0.00005460616,0.00005418276,0.0001327695],"domain_scores_gemma":[0.9998698,0.00003108193,0.00002723512,0.00001488236,0.00001047304,0.00004648469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003809882,0.0002689549,0.0001110609,0.00004880524,0.000005982552,0.00002658642,0.00001918569,0.0001252799,0.996732,0.00004270552,0.0000667606,0.002171831],"study_design_scores_gemma":[0.000096697,0.003226235,0.002204614,0.00001172968,0.00002201384,0.0001755353,0.00003033087,0.002680352,0.9899012,0.00004587226,0.001600376,0.000005077913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968978,0.0006831087,0.0009854258,0.00005223382,0.00002761592,0.00005044655,0.0001249343,0.0001129205,0.001065616],"genre_scores_gemma":[0.9960491,0.0003284976,0.001280593,0.00007899484,0.00002836482,0.0000906982,0.0003132487,0.00002127606,0.001809234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001812783,"threshold_uncertainty_score":0.006064355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00693551193680826,"score_gpt":0.2221695433535521,"score_spread":0.2152340314167438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}