{"id":"W2953701154","doi":"10.1002/hep.30839","title":"Type 3 Inositol 1,4,5‐Trisphosphate Receptor Is Increased and Enhances Malignant Properties in Cholangiocarcinoma","year":2019,"lang":"en","type":"article","venue":"Hepatology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Calgary","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health","keywords":"Endoplasmic reticulum; Inositol trisphosphate receptor; Biology; Cell biology; Mitochondrion; Inositol; Calcium signaling; Cancer research; Receptor; Signal transduction; Pathology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000812408,0.0001375966,0.0002005577,0.0002951554,0.0001733778,0.0002050206,0.00005789986,0.0002438593,0.001582225],"category_scores_gemma":[0.0001200839,0.0001340469,0.0002323375,0.0002526705,0.0001809429,0.0001257971,0.0001628559,0.0004079426,0.0002748522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001404253,"about_ca_system_score_gemma":0.0001102677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000435686,"about_ca_topic_score_gemma":0.0005819039,"domain_scores_codex":[0.9999145,0.00001103934,0.000007068238,0.00001293518,0.00002675462,0.0000277201],"domain_scores_gemma":[0.9998642,0.00001692511,0.00004125796,0.00001160998,0.00001625648,0.00004973941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003019538,0.00002412636,0.005010869,0.00003249047,0.00001063413,0.000633242,0.00003209443,0.00001593813,0.9927543,0.00004320097,0.00009146909,0.001049788],"study_design_scores_gemma":[0.00006034966,0.0006200839,0.4985179,0.00001312098,0.0001067228,0.008725351,0.000325405,0.0007990637,0.4857853,0.0002321384,0.004795752,0.00001866687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979692,0.0006302583,0.000475519,0.0000814914,0.00001420785,0.000007166543,0.0001119101,0.00005287481,0.0006574684],"genre_scores_gemma":[0.9982305,0.0003619592,0.0002232952,0.00004722025,0.000008601061,0.00001032011,0.0001452628,0.00001130616,0.0009616564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001582225,"threshold_uncertainty_score":0.005293131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01262410771307823,"score_gpt":0.226829507495469,"score_spread":0.2142053997823907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}