{"id":"W2953718791","doi":"10.3390/pharmaceutics11070302","title":"Controlled Drug Delivery Systems for Oral Cancer Treatment—Current Status and Future Perspectives","year":2019,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":168,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Medicine; Drug delivery; Cancer; Malignancy; Head and neck cancer; Disease; Intensive care medicine; Head and neck squamous-cell carcinoma; Radiation therapy; Drug; Chronotherapy (sleep phase); Biopharmaceutical; Oncology; Bioinformatics; Pharmacology; Internal medicine; Circadian rhythm; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001134285,0.0007443599,0.002277872,0.0001748042,0.00007596795,0.0001126852,0.0001673389,0.0001957707,0.00002451343],"category_scores_gemma":[0.000005164395,0.0005604808,0.0004857902,0.0001502033,0.00004937474,0.0001244689,0.00002876954,0.0003566931,0.00001693558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001518429,"about_ca_system_score_gemma":0.0003215997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002488165,"about_ca_topic_score_gemma":0.00001246998,"domain_scores_codex":[0.9982001,0.00004185248,0.0005316032,0.0003772819,0.0001806086,0.0006685376],"domain_scores_gemma":[0.9989334,0.0002823869,0.000192353,0.0002673022,0.0001083219,0.0002162691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008781882,0.00004189419,0.000005317165,0.03223068,0.002234782,0.000002180714,0.000590077,0.000340742,0.000003829167,0.00008720999,0.0007367109,0.9636388],"study_design_scores_gemma":[0.005058319,0.00004053344,1.394963e-7,0.001747214,0.00562997,0.00000503036,0.0002046619,0.00630901,0.000006772913,0.000005486046,0.9804158,0.0005771171],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006220633,0.9857179,0.00009184189,0.000006112965,0.007256947,0.004527745,0.002066012,0.0002042977,0.00006693637],"genre_scores_gemma":[0.000067222,0.9962611,0.00004866838,0.000005671035,0.001761284,0.001244788,0.0001421689,0.0002089761,0.0002600897],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.979679,"threshold_uncertainty_score":0.9996847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08307672444134975,"score_gpt":0.3833786094744092,"score_spread":0.3003018850330594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}