{"id":"W2953842309","doi":"10.1039/c9pp00162j","title":"A dormant BODIPY-acrolein singlet oxygen photosensitizer intracellularly activated upon adduct formation with cysteine residues","year":2019,"lang":"en","type":"article","venue":"Photochemical & Photobiological Sciences","topic":"Luminescence and Fluorescent Materials","field":"Materials Science","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Photosensitizer; Singlet oxygen; BODIPY; Photochemistry; Moiety; Chemistry; Adduct; Quenching (fluorescence); HeLa; Singlet state; Excited state; Fluorescence; Oxygen; Stereochemistry; Organic chemistry; Biochemistry; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001642742,0.0002617085,0.0001884764,0.0001080046,0.0001386749,0.000177979,0.0002625728,0.000334291,0.001470637],"category_scores_gemma":[0.0001290061,0.00009888985,0.0001370949,0.0001322536,0.0002270046,0.0002509647,0.0001932775,0.0004192135,0.0002159836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002570145,"about_ca_system_score_gemma":0.0002039164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000301849,"about_ca_topic_score_gemma":0.0004560094,"domain_scores_codex":[0.9999084,0.000009567492,0.00000443351,0.00003229657,0.00001724142,0.00002803535],"domain_scores_gemma":[0.9998894,0.00001813506,0.00003439126,0.00001892056,0.00001442781,0.00002472109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009182849,0.000008617563,0.00004921111,0.00001568174,0.000002082245,0.00002929031,0.000009996463,0.00001498414,0.9991913,0.00009684299,0.00001574755,0.0004744375],"study_design_scores_gemma":[0.000006799437,0.0001103786,0.0004541275,0.000001097045,0.000004586268,0.00006444197,0.000005755992,0.000211019,0.9986091,0.00002310386,0.0005079731,0.000001633416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952869,0.0003048733,0.003419757,0.00006445288,0.00002837692,0.00001947191,0.00005492272,0.0001016583,0.0007195337],"genre_scores_gemma":[0.9967865,0.0001154079,0.001502524,0.00002409142,0.00000579066,0.0000095003,0.00008646118,0.00001163111,0.001458077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001470637,"threshold_uncertainty_score":0.004919708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01540559758921655,"score_gpt":0.2330399573446885,"score_spread":0.217634359755472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}