{"id":"W2953923628","doi":"10.1016/j.scitotenv.2019.06.532","title":"Shape-dependent toxicity of alumina nanoparticles in rat astrocytes","year":2019,"lang":"en","type":"article","venue":"The Science of The Total Environment","topic":"Nanoparticles: synthesis and applications","field":"Materials Science","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Beijing University of Technology; National Natural Science Foundation of China","keywords":"Neurotoxicity; Metabolome; Toxicity; Apoptosis; Cytotoxicity; Inflammation; Chemistry; Nanorod; Nanoparticle; Microglia; Biochemistry; Cell biology; Pharmacology; Biophysics; Biology; Nanotechnology; In vitro; Materials science; Immunology; Metabolite","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00110882,0.00008150693,0.0001381061,0.00002632555,0.000110006,0.00001964344,0.0008248721,0.00001553737,0.0005104087],"category_scores_gemma":[0.00003434953,0.00004462111,0.00004889759,0.000198454,0.001006444,0.0001380878,0.00041529,0.00004678244,0.0001483056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006592723,"about_ca_system_score_gemma":0.00003698503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003552897,"about_ca_topic_score_gemma":0.000001574351,"domain_scores_codex":[0.9986443,0.00006361966,0.0002751033,0.0002267264,0.0005463873,0.0002438776],"domain_scores_gemma":[0.999097,0.00007274873,0.0001648387,0.0006181462,0.000008747885,0.00003847351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001005501,0.0001114334,0.0002489789,0.000004126767,8.815409e-7,5.070718e-8,0.0002023523,0.01040035,0.98783,0.0008721905,0.000003180852,0.0003163909],"study_design_scores_gemma":[0.0001161347,0.00004438507,0.01708029,0.00001916177,0.000006734804,0.000001799706,0.0002724511,0.001882471,0.9802571,0.0002584106,0.000007066287,0.00005401022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988304,0.0000469062,0.000004017671,0.0005140718,0.00008142294,0.0003084651,0.000006020964,0.000005195512,0.0002034547],"genre_scores_gemma":[0.9995379,0.000006991562,0.0002133476,0.000009412823,0.000007048455,0.00001850844,5.264561e-8,0.00000429066,0.0002024877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01683131,"threshold_uncertainty_score":0.5588617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01001893086748745,"score_gpt":0.2102823933446967,"score_spread":0.2002634624772093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}